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MAP/microtubule affinity regulating kinase 2

Summary

Gene Symbol

Mark2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

13728

PubChem

13728

Alliance of Genome Resources

MGI:99638

Annotation

Keyword

ATP-binding
Alternative splicing
Cell membrane
Cell projection
Cytoskeleton
Developmental protein
Differentiation
Lipid-binding
Magnesium
Metal-binding
Phosphoprotein
Proteomics identification
Reference proteome
Serine/threonine-protein kinase
Wnt signaling pathway

Proteins

Displaying **all 6** entries
UniProt	Protein Name
Q05512	ELKL motif kinase 1 MAP/microtubule affinity-regulating kinase 2 PAR1 homolog PAR1 homolog b
E9PYX3	ELKL motif kinase 1 MAP/microtubule affinity-regulating kinase 2
E9QMP6	ELKL motif kinase 1 MAP/microtubule affinity-regulating kinase 2
Q3T9A3	ELKL motif kinase 1 MAP/microtubule affinity-regulating kinase 2
A0A0R4J0B1	ELKL motif kinase 1 MAP/microtubule affinity-regulating kinase 2
A0A0R4J227	ELKL motif kinase 1 MAP/microtubule affinity-regulating kinase 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 26 in total

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GO Term	Evidence Code	PMID
microtubule cytoskeleton organization	IBA
neuron migration	ISS
neuron migration	ISO
chromatin remodeling	IEA
protein phosphorylation	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization

establishment or maintenance of cell polarity [inference]

establishment of cell polarity

establishment or maintenance of bipolar cell polarity [inference]

establishment or maintenance of apical/basal cell polarity [inference]

establishment or maintenance of epithelial cell apical/basal polarity

establishment or maintenance of cell polarity regulating cell shape

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

intracellular signal transduction

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cell motility [inference]

cell migration [inference]

neuron migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

axon development

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape [inference]

establishment or maintenance of cell polarity regulating cell shape

regulation of axonogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

intracellular signal transduction

regulation of microtubule-based process [inference]

regulation of microtubule cytoskeleton organization

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of organelle organization [inference]

regulation of cytoskeleton organization

regulation of microtubule cytoskeleton organization

regulation of synapse organization [inference]

regulation of postsynapse organization

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of biological quality [inference]

regulation of cell shape [inference]

establishment or maintenance of cell polarity regulating cell shape

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
nucleus	IDA	15950600
nucleoplasm	ISO
cytoplasm	ISS
cytoplasm	ISO
cytoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoplasm

cytoplasm

cell cortex [inference]

cell cortex region [inference]

basal cortex

cytoplasmic region [inference]

cell cortex region [inference]

basal cortex

membrane

plasma membrane

lateral plasma membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

actin filament

Displaying entries **6 - 10** of 31 in total

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GO Term	Evidence Code	PMID
DNA-dependent protein kinase activity	IEA
AMP-activated protein kinase activity	IEA
eukaryotic translation initiation factor 2alpha kinase activity	IEA
ribosomal protein S6 kinase activity	IEA
ATP binding	ISS