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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
corticotropin releasing hormone receptor 1
Summary
- Gene Symbol
-
- CRHR1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Endosome
- G-protein coupled receptor
- Glycoprotein
- Phosphoprotein
- Proteomics identification
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway | ||
| adrenal gland development | ||
| cellular response to corticotropin-releasing hormone stimulus | ||
| behavioral response to ethanol | ||
| parturition |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of monoatomic ion transport [inference]
negative regulation of transport [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of transmembrane transport [inference]
negative regulation of cellular process [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| postsynaptic density membrane | ||
| plasma membrane | ||
| endosome | ||
| neuron projection |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| corticotrophin-releasing factor receptor activity | ||
| G protein-coupled peptide receptor activity | ||
| corticotropin-releasing hormone binding | ||
| corticotropin-releasing hormone receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- diuretic hormone receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050696 | fetal alcohol spectrum disorder | |
| DOID:10763 | hypertension | |
| DOID:12918 | thromboangiitis obliterans | |
| DOID:1596 | depressive disorder | |
| DOID:2841 | asthma | |
| DOID:3083 | chronic obstructive pulmonary disease | |
| DOID:3877 | functional colonic disease | |
| DOID:4483 | rhinitis | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9778 | irritable bowel syndrome |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 12921 | MGI:88498 | MOUSE05672 | ||
| 36368 | FB:FBgn0033744 | |||
| 36601 | FB:FBgn0033932 | |||
| 58959 | RGD:61276 | RATNO00452 | ||
| 373580 | Xenbase:XB-GENE-968270 | |||
| 397426 | PIGXX02084 | |||
| 567940 | ZFIN:ZDB-GENE-081231-1 | DANRE30869 | ||
| 574095 | MACMU14767 | |||
| 610380 | CANLF18520 | |||
| 100024819 | MONDO11972 |
