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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
CRK proto-oncogene, adaptor protein
Summary
- Gene Symbol
-
- CRK
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cell membrane
- Cytoplasm
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Repeat
- SH2 domain
- SH3 domain
- Proteins
| UniProt | Protein Name |
|---|---|
| P46108 |
|
| A0A0S2Z3Q4 |
|
| A0A0S2Z3K9 |
|
| L7RT18 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of dendrite development | ||
| helper T cell diapedesis | ||
| postsynaptic specialization assembly | ||
| cell population proliferation | ||
| actin cytoskeleton organization |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| protein-containing complex | ||
| plasma membrane | ||
| neuromuscular junction | ||
| actin cytoskeleton |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- crk
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cell migration |
| receptor tyrosine kinase binding |
| signaling adaptor activity |
| InterPro |
|---|
| CRK, N-terminal SH3 domain |
| SH2 domain superfamily |
| SH2 domain |
| SH3 domain |
| SH3-like domain superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:90 | degenerative disc disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 12928 | MGI:88508 | MOUSE03431 | ||
| 43775 | FB:FBgn0024811 | |||
| 54245 | RGD:2405 | RATNO01015 | ||
| 176968 | WB:WBGene00000416 | |||
| 398951 | Xenbase:XB-GENE-996363 | |||
| 445234 | ZFIN:ZDB-GENE-040801-148 | DANRE08361 | ||
| 448023 | Xenbase:XB-GENE-996357 | |||
| 701185 | MACMU14221 | |||
| 747142 | 9598_0:0045c6 | PANTR13173 | ||
| 100012317 | MONDO15286 |
