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laminin subunit alpha 5

Summary

Gene Symbol

Lama5

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

140433

PubChem

140433

Alliance of Genome Resources

RGD:621023

Annotation

Keyword

Basement membrane
Coiled coil
Disulfide bond
Glycoprotein
Laminin EGF-like domain
Reference proteome
Repeat
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6KMB1
F1MAN8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
branching involved in ureteric bud morphogenesis	ISO
morphogenesis of a polarized epithelium	ISO
neural crest cell migration	ISO
kidney development	ISO
hair follicle development	ISO

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell-substrate adhesion [inference]

substrate adhesion-dependent cell spreading

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

cell motility [inference]

cell migration

ameboidal-type cell migration [inference]

mesenchymal cell migration [inference]

neural crest cell migration

trunk neural crest cell migration

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

postsynapse organization

multicellular organismal process [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

branching involved in salivary gland morphogenesis

molting cycle process [inference]

hair cycle process [inference]

hair follicle development

developmental process [inference]

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

branching involved in salivary gland morphogenesis

animal organ morphogenesis

odontogenesis [inference]

odontogenesis of dentin-containing tooth

skeletal system morphogenesis

tube morphogenesis [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

embryonic morphogenesis [inference]

morphogenesis of embryonic epithelium

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

branching involved in salivary gland morphogenesis

anatomical structure development [inference]

animal organ development [inference]

muscle structure development [inference]

muscle organ development

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

regulation of developmental process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

regulation of cell adhesion

regulation of cell population proliferation [inference]

regulation of epithelial cell proliferation

regulation of cell motility [inference]

regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
basement membrane	ISO
basement membrane	IBA
laminin-5 complex	IDA	9417868
extracellular space	ISO
extracellular matrix	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

laminin complex [inference]

cellular anatomical entity [inference]

extracellular region [inference]

synaptic cleft

extracellular space

cell junction [inference]

synapse [inference]

external encapsulating structure [inference]

extracellular matrix

collagen-containing extracellular matrix [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
integrin binding	ISO
extracellular matrix structural constituent	IBA
receptor ligand activity	ISO
cell adhesion mediator activity	ISO

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cell adhesion molecule binding [inference]

protein-containing complex binding [inference]

integrin binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Laminin subunit alpha

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 2** entries
InterPro
EGF-like domain
Laminin-type EGF domain

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
laminin-5 complex	PMID:9417868

Ortholog

Displaying entries **1 - 10** of 33 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	3909	FB:FBgn0002526
Homo sapiens	3911	Xenbase:XB-GENE-1007923	HUMAN57819
Drosophila melanogaster	16774	FB:FBgn0002526
Mus musculus	16776	Xenbase:XB-GENE-1007923	MOUSE31722
Xenopus tropicalis	38723	Xenbase:XB-GENE-1007923
Xenopus tropicalis	140433	Xenbase:XB-GENE-1007923
Xenopus tropicalis	177956	Xenbase:XB-GENE-1007923
Danio rerio	321243		DANRE24521
Monodelphis domestica	100026192		MONDO01915
Equus caballus	100058057		HORSE21003