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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
Summary
- Gene Symbol
-
- Kcnn2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Calmodulin-binding
- Ion channel
- Ion transport
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| B4YDY0 |
|
| P58390 |
|
| A0A1B0GT12 |
|
| Q8C7F3 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of potassium ion transmembrane transport | ||
| ion transmembrane transport | ||
| membrane repolarization during atrial cardiac muscle cell action potential | ||
| potassium ion transport | ||
| positive regulation of potassium ion transport |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| postsynaptic membrane | ||
| sarcolemma | ||
| T-tubule | ||
| neuronal cell body |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| calmodulin binding | ||
| calcium-activated potassium channel activity | ||
| protein domain specific binding | ||
| protein homodimerization activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- small conductance calcium-activated potassium channel protein 2
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| calcium-activated potassium channel activity |
| calmodulin binding |
| monoatomic ion transport |
| small conductance calcium-activated potassium channel activity |
| InterPro |
|---|
| Calmodulin-binding domain |
| Potassium channel domain |
| Potassium channel, calcium-activated, SK |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060957 | myoclonic dystonia 34 | |
| DOID:14330 | Parkinson's disease | |
| DOID:4990 | essential tremor |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 3781 | HGNC:6291 | HUMAN80326 | ||
| 31456 | FB:FBgn0029761 | |||
| 54262 | 10116_1:004ef7 | RGD:2963 | ||
| 172602 | WB:WBGene00008570 | |||
| 404177 | BOVIN00333 | |||
| 462006 | PANTR35927 | |||
| 474640 | CANLF02006 | |||
| 564698 | ZFIN:ZDB-GENE-091116-41 | |||
| 695374 | MACMU37859 | |||
| 100016183 | MONDO16105 |
