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N-acetylneuraminic acid phosphatase

Summary

Gene Symbol

NANP

Aliases

MGC26833
dJ694B14.3

Organism

Homo sapiens (human)

External Links

NCBI Gene

140838

HGNC

16140

KEGG Gene ID

hsa:140838

PubChem

140838

Alliance of Genome Resources

HGNC:16140

Annotation

Keyword

3D-structure
Carbohydrate metabolism
Hydrolase
Magnesium
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8TBE9	Haloacid dehalogenase-like hydrolase domain-containing protein 4 Neu5Ac-9-Pase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
N-acetylneuraminate biosynthetic process	IBA IDA	16237198
dephosphorylation	IBA
N-acetylglucosamine biosynthetic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

amide metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

amide biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

organonitrogen compound biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

amino sugar biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

glucosamine-containing compound biosynthetic process [inference]

N-acetylglucosamine biosynthetic process

organonitrogen compound biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

amino sugar biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

glucosamine-containing compound biosynthetic process [inference]

N-acetylglucosamine biosynthetic process

glucosamine-containing compound metabolic process [inference]

N-acetylglucosamine metabolic process [inference]

N-acetylglucosamine biosynthetic process

glucosamine-containing compound biosynthetic process [inference]

N-acetylglucosamine biosynthetic process

carbohydrate derivative biosynthetic process [inference]

amino sugar biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

glucosamine-containing compound biosynthetic process [inference]

N-acetylglucosamine biosynthetic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

organonitrogen compound biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

amino sugar biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

glucosamine-containing compound biosynthetic process [inference]

N-acetylglucosamine biosynthetic process

organonitrogen compound biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate biosynthetic process

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

N-acetylneuraminate biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol
cellular_component	ND

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying 1 entry
GO Term	Evidence Code	PMID
N-acylneuraminate-9-phosphatase activity	IBA IDA	16237198

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

N-acylneuraminate-9-phosphatase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01097

Name

N-acylneuraminate-9-phosphatase [EC:3.1.3.29]

References

16237198

Rhea

H₂O + an N-acylneuraminate 9-phosphate

phosphate + an N-acylneuraminate

Enzyme

3.1.3.29

PMID

16237198

Disease

Disease Ontology

Displaying **all 7** entries
DO ID	Disease Name	Source
DOID:1107	esophageal carcinoma	DisGeNET
DOID:12365	malaria	DisGeNET
DOID:1443	cerebral degeneration	DisGeNET
DOID:162	cancer	DisGeNET
DOID:5041	esophageal cancer	DisGeNET
DOID:5672	large intestine cancer	DisGeNET
DOID:9256	colorectal cancer	DisGeNET

Ortholog

Displaying entries **1 - 10** of 75 in total

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Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	31500	FB:FBgn0029801
Callorhinchus milii	103178930		CALMI16680
Latimeria chalumnae	102347112		LATCH07149
Danio rerio	553795	ZFIN:ZDB-GENE-050522-94	DANRE51340
Astyanax mexicanus	103036320		ASTMX12102
Ictalurus punctatus	108263708		ICTPU26559
Electrophorus electricus	113579924		ELEEL24478
Salmo salar	106604799		SALSA09307
Salmo trutta	115153033		SALTR07183
Oryzias latipes	101159461		ORYLA04657

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024