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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fas cell surface death receptor
Summary
- Gene Symbol
-
- Fas
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Apoptosis
- Calmodulin-binding
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Palmitate
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to toxic substance | ||
| positive regulation of release of cytochrome c from mitochondria | ||
| lymphocyte apoptotic process | ||
| immunoglobulin production | ||
| regulation of stress-activated MAPK cascade |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| secretory granule | ||
| sarcolemma | ||
| death-inducing signaling complex | ||
| apical plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| kinase binding | ||
| protein binding | ||
| calmodulin binding | ||
| protein-containing complex binding | ||
| protease binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- tumor necrosis factor receptor superfamily member 6
- Functional Category
-
- I: Lipid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| InterPro |
|---|
| Death domain |
| Death-like domain superfamily |
| Fas receptor, N-terminal |
| Fas receptor |
| TNFR/NGFR cysteine-rich region |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050523 | adult T-cell leukemia/lymphoma | |
| DOID:0050697 | chorioamnionitis | |
| DOID:0050908 | myelodysplastic syndrome | |
| DOID:0060071 | pre-malignant neoplasm | |
| DOID:0060108 | brain glioma | |
| DOID:0060704 | lymphoproliferative syndrome | |
| DOID:0080797 | nasal type extranodal NK/T-cell lymphoma | |
| DOID:0081267 | graft-versus-host disease | |
| DOID:10223 | dermatomyositis | |
| DOID:10283 | prostate cancer |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 355 | HGNC:11920 | HUMAN02087 | ||
| 246097 | 10116_1:000477 | RGD:619831 | RATNO18988 | |
| 282488 | BOVIN21145 | |||
| 486469 | CANLF10679 | |||
| 493881 | FELCA26636 | |||
| 738331 | PANTR01106 | |||
| 768248 | ZFIN:ZDB-GENE-061019-2 | DANRE12971 | ||
| 100071639 | HORSE15953 | |||
| 100124750 | Xenbase:XB-GENE-940178 | |||
| 100144426 | SHEEP11422 |
