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follicle stimulating hormone beta

Summary

Gene Symbol

Fshb

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14308

PubChem

14308

Alliance of Genome Resources

MGI:95582

Annotation

Keyword

Disulfide bond
Glycoprotein
Hormone
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A0F7RQR1	Follicle-stimulating hormone beta subunit Follitropin beta chain
Q60687	Follicle-stimulating hormone beta subunit Follitropin beta chain

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
spermatogenesis	IGI	11459797
positive regulation of bone resorption	IMP	16630814
regulation of osteoclast differentiation	IMP	16630814
positive regulation of steroid biosynthetic process	IEA ISO
G protein-coupled receptor signaling pathway	ISO ISS

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

G protein-coupled receptor signaling pathway

follicle-stimulating hormone signaling pathway

cell population proliferation [inference]

epithelial cell proliferation [inference]

Sertoli cell proliferation

cellular process involved in reproduction in multicellular organism [inference]

follicle-stimulating hormone signaling pathway

reproductive process [inference]

developmental process involved in reproduction [inference]

cellular process involved in reproduction in multicellular organism [inference]

follicle-stimulating hormone signaling pathway

ovulation cycle process [inference]

follicle-stimulating hormone signaling pathway

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

Sertoli cell proliferation

developmental process [inference]

developmental process involved in reproduction [inference]

anatomical structure development [inference]

ovarian follicle development

rhythmic process [inference]

ovulation cycle process [inference]

follicle-stimulating hormone signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

regulation of osteoclast differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

regulation of osteoclast differentiation

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid biosynthetic process [inference]

positive regulation of steroid biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of lipid biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of steroid biosynthetic process

regulation of steroid biosynthetic process [inference]

positive regulation of steroid biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid biosynthetic process [inference]

positive regulation of steroid biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid metabolic process [inference]

positive regulation of steroid metabolic process [inference]

positive regulation of steroid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of steroid biosynthetic process

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of steroid metabolic process [inference]

positive regulation of steroid metabolic process [inference]

positive regulation of steroid biosynthetic process

regulation of steroid biosynthetic process [inference]

positive regulation of steroid biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of steroid metabolic process [inference]

positive regulation of steroid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of steroid biosynthetic process

regulation of lipid biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of steroid biosynthetic process

regulation of steroid biosynthetic process [inference]

positive regulation of steroid biosynthetic process

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of signaling receptor activity

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid biosynthetic process [inference]

positive regulation of steroid biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of lipid metabolic process [inference]

positive regulation of steroid metabolic process [inference]

positive regulation of steroid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of steroid biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of multicellular organismal process [inference]

positive regulation of bone resorption

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of signaling receptor activity

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of cell development [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

regulation of osteoclast differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

regulation of osteoclast differentiation

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

regulation of osteoclast differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

regulation of osteoclast differentiation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

G protein-coupled receptor signaling pathway

follicle-stimulating hormone signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of signaling receptor activity

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cell differentiation [inference]

regulation of cell development [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

regulation of osteoclast differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

regulation of osteoclast differentiation

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of multicellular organismal process [inference]

regulation of tissue remodeling [inference]

regulation of bone remodeling [inference]

regulation of bone resorption [inference]

positive regulation of bone resorption

positive regulation of multicellular organismal process [inference]

positive regulation of bone resorption

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

regulation of osteoclast differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

regulation of osteoclast differentiation

regulation of molecular function [inference]

regulation of signaling receptor activity

Displaying **all 3** entries
GO Term	Evidence Code	PMID
follicle-stimulating hormone complex	ISO ISS
extracellular space	IBA ISO ISS
cytoplasm	IBA IDA ISO	24739304

GO Hierarchy

cellular component

protein-containing complex [inference]

pituitary gonadotropin complex [inference]

follicle-stimulating hormone complex

cellular anatomical entity [inference]

Displaying 1 entry
GO Term	Evidence Code	PMID
follicle-stimulating hormone activity	IBA ISO ISS

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor ligand activity [inference]

hormone activity [inference]

follicle-stimulating hormone activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity [inference]

follicle-stimulating hormone activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity [inference]

follicle-stimulating hormone activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

V(D)J recombination-activating protein 1

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 3** entries
Gene Ontology
follicle-stimulating hormone activity
follicle-stimulating hormone signaling pathway
hormone activity

Displaying **all 4** entries
InterPro
Cystine-knot cytokine
Glycoprotein hormone subunit beta
Gonadotropin, beta subunit, conserved site
Gonadotropin, beta subunit

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0090088	hypogonadotropic hypogonadism 24 without anosmia	Alliance of Genome Resources
DOID:13938	amenorrhea	Alliance of Genome Resources
DOID:2945	severe acute respiratory syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of **119** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Callithrix jacchus	100398993			CALJA04059
Pongo abelii	100444274			PONAB03590
Ailuropoda melanoleuca	100482376			AILME05589
Xenopus tropicalis	100495812		Xenbase:XB-GENE-484695
Anolis carolinensis	100568157			ANOCA00415
Nomascus leucogenys	100599170			NOMLE10829
Loxodonta africana	100666748			LOXAF12457
Cricetulus griseus	100689453	10029_0:003d8e		CRIGR03522
Capra hircus	100861299			CAPHI05492
Sarcophilus harrisii	100913282			SARHA07706

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements