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colony stimulating factor 1 receptor

Summary

Gene Symbol

CSF1R

Organism

Homo sapiens (human)

External Links

NCBI Gene

1436

PubChem

1436

Alliance of Genome Resources

HGNC:2433

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Cell membrane
Disease variant
Disulfide bond
Glycoprotein
Immunoglobulin domain
Inflammatory response
Innate immunity
Neurodegeneration
Phosphoprotein
Proto-oncogene
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P07333	CSF-1 receptor Proto-oncogene c-Fms

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 43 in total

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GO Term	Evidence Code	PMID
positive regulation of cell population proliferation	IMP	20504948
positive regulation of cell motility	IMP	15117969
cell population proliferation	IMP	7683918
response to ischemia	ISS	8922060
positive regulation of protein phosphorylation	IMP	20504948

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

cytokine-mediated signaling pathway

macrophage colony-stimulating factor signaling pathway

cell population proliferation

glial cell proliferation [inference]

microglial cell proliferation

leukocyte proliferation [inference]

macrophage proliferation [inference]

microglial cell proliferation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

monocyte differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

neuron differentiation [inference]

central nervous system neuron differentiation [inference]

forebrain neuron differentiation

cell development [inference]

hemopoiesis

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to macrophage colony-stimulating factor stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

ruffle organization

cell junction organization [inference]

cell junction maintenance [inference]

cell-cell junction maintenance

cell-cell junction organization [inference]

cell-cell junction maintenance

cellular component maintenance [inference]

cell junction maintenance [inference]

cell-cell junction maintenance

multicellular organismal process [inference]

multicellular organism development

developmental process [inference]

anatomical structure morphogenesis [inference]

tube morphogenesis [inference]

epithelial tube morphogenesis [inference]

mammary gland duct morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

epithelial tube morphogenesis [inference]

mammary gland duct morphogenesis

anatomical structure development [inference]

cell development [inference]

hemopoiesis

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

monocyte differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

neuron differentiation [inference]

central nervous system neuron differentiation [inference]

forebrain neuron differentiation

cell development [inference]

hemopoiesis

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with symbiont [inference]

modulation by host of symbiont process [inference]

modulation by host of viral process [inference]

positive regulation by host of viral process

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

response to ischemia

defense response [inference]

inflammatory response

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to macrophage colony-stimulating factor [inference]

cellular response to macrophage colony-stimulating factor stimulus

cellular response to cytokine stimulus

cellular response to macrophage colony-stimulating factor stimulus

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to macrophage colony-stimulating factor stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to macrophage colony-stimulating factor stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to macrophage colony-stimulating factor stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of macrophage chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of granulocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of mononuclear cell migration [inference]

positive regulation of macrophage chemotaxis

regulation of macrophage migration

regulation of macrophage chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

regulation of chemokine production [inference]

positive regulation of chemokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

regulation of chemokine production [inference]

positive regulation of chemokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

regulation of chemokine production [inference]

positive regulation of chemokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of cell motility

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of macrophage chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of granulocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of macrophage chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of granulocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of mononuclear cell migration [inference]

positive regulation of macrophage chemotaxis

regulation of macrophage migration

regulation of macrophage chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

positive regulation of cell motility

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of cell motility

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of macrophage proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of cell motility

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of macrophage chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of granulocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

cytokine-mediated signaling pathway

macrophage colony-stimulating factor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

regulation of chemokine production [inference]

positive regulation of chemokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of macrophage proliferation

negative regulation of cell population proliferation

regulation of leukocyte proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of macrophage proliferation

regulation of macrophage proliferation [inference]

positive regulation of macrophage proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of macrophage proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

positive regulation of cell motility

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of macrophage chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of granulocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

regulation of mononuclear cell migration [inference]

positive regulation of macrophage chemotaxis

regulation of macrophage migration

regulation of macrophage chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

positive regulation of cell motility

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of macrophage chemotaxis

positive regulation of macrophage migration [inference]

positive regulation of macrophage chemotaxis

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

regulation of chemokine production [inference]

positive regulation of chemokine production

regulation of tissue remodeling [inference]

regulation of bone remodeling [inference]

regulation of bone resorption

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production

regulation of biological quality [inference]

regulation of cell shape

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

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GO Term	Evidence Code	PMID
receptor complex	IBA
intracellular membrane-bounded organelle	IDA
plasma membrane	IBA IDA TAS
CSF1-CSF1R complex	IBA ISS	19017797
cell surface	ISS	8922060

GO Hierarchy

cellular component

protein-containing complex [inference]

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

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GO Term	Evidence Code	PMID
protein binding	IPI	22153499 22483114 22902366 23478061 26235028 35384245
macrophage colony-stimulating factor receptor activity	IBA IMP ISS	20504948 7683918
protein phosphatase binding	IEA
growth factor binding	IBA
protein tyrosine kinase activity	TAS	23392676

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity [inference]

macrophage colony-stimulating factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

macrophage colony-stimulating factor receptor activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity [inference]

macrophage colony-stimulating factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

macrophage colony-stimulating factor receptor activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity [inference]

macrophage colony-stimulating factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

macrophage colony-stimulating factor receptor activity

binding [inference]

protein binding

growth factor binding

enzyme binding [inference]

phosphatase binding [inference]

protein phosphatase binding

cytokine binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

macrophage colony-stimulating factor receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

vascular endothelial growth factor receptor

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ATP binding
growth factor binding
metal ion binding
nucleotide binding
positive regulation of cell migration
transmembrane receptor protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase signaling pathway

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InterPro
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine-threonine/tyrosine-protein kinase, catalytic domain
Tyrosine-protein kinase, active site
Tyrosine-protein kinase, catalytic domain

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0070343	CSF1R-related brain malformation and osteopetrosis	Alliance of Genome Resources
DOID:0080006	bone development disease	Alliance of Genome Resources
DOID:0080199	colorectal carcinoma	Alliance of Genome Resources
DOID:0080523	adult-onset leukoencephalopathy with axonal spheroids and pigmented glia	Alliance of Genome Resources
DOID:10534	stomach cancer	Alliance of Genome Resources
DOID:13139	crescentic glomerulonephritis	Alliance of Genome Resources
DOID:1324	lung cancer	Alliance of Genome Resources
DOID:1612	breast cancer	Alliance of Genome Resources
DOID:162	cancer	Alliance of Genome Resources
DOID:234	colon adenocarcinoma	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	12978		MGI:1339758	MOUSE23367
Drosophila melanogaster	34127		FB:FBgn0032006
Danio rerio	64274		ZFIN:ZDB-GENE-001205-1	DANRE07587
Caenorhabditis elegans	186632		WB:WBGene00006897
Rattus norvegicus	307403		RGD:2425	RATNO13472
Pan troglodytes	462187	9598_0:001993		PANTR36554
Canis lupus familiaris	489188			CANLF14927
Xenopus tropicalis	493543		Xenbase:XB-GENE-6257851
Felis catus	493706			FELCA00791
Bos taurus	509418			BOVIN33740

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements