GlyCosmos Portal

Submissions

laccase domain containing 1

Summary

Gene Symbol

LACC1

Aliases

FAMIN
FLJ38725
fatty acid metabolism–immunity nexus

Organism

Homo sapiens (human)

External Links

NCBI Gene

144811

HGNC

26789

PubChem

144811

Alliance of Genome Resources

HGNC:26789

Annotation

Keyword

Acetylation
Cytoplasm
Endoplasmic reticulum
Hydrolase
Inflammatory response
Innate immunity
Metal-binding
Nucleus
Peroxisome
Phosphoprotein
Reference proteome
Transferase
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8IV20	Adenosine deaminase LACC1 Fatty acid metabolism-immunity nexus Guanosine phosphorylase LACC1 Laccase domain-containing protein 1 S-methyl-5'-thioadenosine phosphorylase LACC1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
pattern recognition receptor signaling pathway	IDA	28593945 31875558
inflammatory response	IEA
innate immune response	IEA
positive regulation of cytokine production involved in immune response	IDA	28593945
regulation of cellular pH	IDA	31978345

GO Hierarchy

biological process

immune system process [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response [inference]

innate immune response

cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

monoatomic cation homeostasis [inference]

regulation of pH [inference]

regulation of cellular pH

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

biological regulation [inference]

regulation of pH [inference]

regulation of cellular pH

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of small molecule metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of inflammatory response

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleus	ISS
endoplasmic reticulum	IDA	31875558
peroxisome	IDA	27478939 27959965

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
adenosine deaminase activity	IDA	31978345
guanosine phosphorylase activity	IDA	31978345
oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor	IDA	27959965 31978345
2'-deoxyadenosine deaminase activity	IEA
purine-nucleoside phosphorylase activity	IDA	31978345

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on diphenols and related substances as donors [inference]

oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor

transferase activity [inference]

glycosyltransferase activity [inference]

pentosyltransferase activity [inference]

purine-nucleoside phosphorylase activity

S-methyl-5-thioadenosine phosphorylase activity

guanosine phosphorylase activity

hydrolase activity [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines [inference]

deaminase activity [inference]

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000179630

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

Rhea

RHEA:13233

guanosine + phosphate

guanine + α-D-ribose 1-phosphate

Enzyme

PMID

RHEA:24408

H₂O + H⁺ + adenosine

inosine + NH₄⁺

Enzyme

3.5.4.4

PMID

RHEA:19805

a purine D-ribonucleoside + phosphate

a purine nucleobase + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:27738

2'-deoxyguanosine + phosphate

guanine + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:27750

2'-deoxyinosine + phosphate

hypoxanthine + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:27642

adenosine + phosphate

adenine + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

27941785

RHEA:36431

a purine 2'-deoxy-D-ribonucleoside + phosphate

a purine nucleobase + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:27638

xanthosine + phosphate

xanthine + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

27941785

RHEA:27646

inosine + phosphate

hypoxanthine + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:11852

S-methyl-5'-thioadenosine + phosphate

adenine + S-methyl-5-thio-α-D-ribose 1-phosphate

Enzyme

2.4.2.28

PMID

RHEA:28190

H₂O + H⁺ + 2'-deoxyadenosine

NH₄⁺ + 2'-deoxyinosine

Enzyme

3.5.4.4

PMID

RHEA:24869

5'-deoxyadenosine + phosphate

adenine + 5-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.28

PMID

6164373

RHEA:27742

2'-deoxyadenosine + phosphate

adenine + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

21672603

Disease

Disease Ontology

Displaying entry **11 - 11** of 11 in total

« First

‹ Prev

1

2
DO ID	Disease Name	Source
DOID:8778	Crohn's disease	DisGeNET

The Human Phenotype Ontology

Displaying entries **11 - 20** of 21 in total

« First

‹ Prev

1

2

3

Next ›

Last »
HPO ID	HPO Term
HP:0002202	Pleural effusion
HP:0002240	Hepatomegaly
HP:0002716	Lymphadenopathy
HP:0002829	Arthralgia
HP:0002960	Autoimmunity
HP:0003493	Antinuclear antibody positivity
HP:0003565	Elevated erythrocyte sedimentation rate
HP:0005681	Juvenile rheumatoid arthritis
HP:0011227	Elevated circulating C-reactive protein concentration
HP:0011463	Childhood onset

Displaying **all 2** entries
Disease ID	Disease Name
ORPHA:85414	systemic-onset juvenile idiopathic arthritis
OMIM:618795	juvenile arthritis due to defect in LACC1

PubChem Disease

MedGen Diseases

Juvenile arthritis due to defect in LACC1

OMIM Phenotypes

JUVENILE ARTHRITIS; JUVAR

KEGG Diseases

Juvenile idiopathic arthritis

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **1 - 10** of 89 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Callorhinchus milii	103177523		CALMI13241
Latimeria chalumnae	102359258		LATCH04855
Danio rerio	100005054	ZFIN:ZDB-GENE-081104-155	DANRE45201
Ictalurus punctatus	108266591		ICTPU31044
Electrophorus electricus	113577125		ELEEL20646
Esox lucius	105016377		ESOLU47237
Salmo salar	106586521		SALSA90204
Salmo trutta	115161055		SALTR15736
Oreochromis niloticus	100708543		ORENI21286
Haplochromis burtoni	102295229		HAPBU25768

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

PubChem Disease

International Collaboration

Acknowledgements