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beta 3-glucosyltransferase

Summary

Gene Symbol

B3GLCT

Aliases

B3GTL
B3Glc-T
beta-1,3-glucosyltransferase

Organism

Homo sapiens (human)

External Links

NCBI Gene

145173

GGDB ID

gg184

HGNC

20207

mRNA

NM_194318

map

13q12.3

Protein

NP_919299

OMIM

610308

KEGG Gene ID

hsa:145173

PubChem

145173

Alliance of Genome Resources

HGNC:20207

Annotation

Keyword

Congenital disorder of glycosylation
Dwarfism
Endoplasmic reticulum
Fucose metabolism
Glycoprotein
Glycosyltransferase
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6Y288	Beta 3-glucosyltransferase Beta-3-glycosyltransferase-like

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
roof of mouth development	IEA
brain development	IEA
protein O-linked fucosylation	TAS
cilium assembly	IEA
camera-type eye development	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

glycosylation [inference]

fucosylation [inference]

protein O-linked fucosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

export from cell [inference]

secretion by cell [inference]

protein secretion

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

brain development

sensory organ development [inference]

eye development [inference]

camera-type eye development

system development [inference]

skeletal system development

appendage development [inference]

limb development

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of localization [inference]

transport [inference]

secretion [inference]

secretion by cell [inference]

protein secretion

organic substance transport [inference]

protein transport [inference]

protein secretion

nitrogen compound transport [inference]

protein transport [inference]

protein secretion

export from cell [inference]

secretion by cell [inference]

protein secretion

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
acetylglucosaminyltransferase activity	IBA
glycosyltransferase activity	TAS

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Uncharacterized protein

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
acetylglucosaminyltransferase activity

Displaying 1 entry
InterPro
Protein of unknown function DUF604

GlycoGene Database (GGDB)

GGDB ID

gg184

Gene Symbol

B3GLCT

Reactions

Displaying 1 entry
Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
UDP-Glc	G96881BQ	[alpha]-pNp	G36855WW	[alpha]-pNp	16899492

Displaying **all 4** entries
Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
UDP-Glc	G61459JW	[beta]-pNp	G70899NZ	[beta]-pNp	16899492
UDP-Glc	G39023AU	[beta]-pNp	G71649FF	[beta]-pNp	16899492
UDP-Glc	G96881BQ	rat F-spondin TSR4	G36855WW	rat F-spondin TSR4	17032646
UDP-Glc	G96881BQ	[alpha]-pNp	G36855WW	[alpha]-pNp	16899492

Displaying entries **1 - 5** of 16 in total

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Donor	Acceptor	Reducing terminal(Acceptor)	Reference
UDP-Gal	G96881BQ	TSR4	17032646
UDP-GalNAc	G96881BQ	TSR4	17032646
UDP-Glc	G96881BQ	[beta]-pNp	16899492
UDP-Glc	G58161NS	[alpha]-pNp	16899492
UDP-Glc	G40696TO	[beta]-pNp	16899492

Orthologous Gene

Displaying 1 entry
Species	Protein	mRNA
Mus musculus	NP_001074673	NM_001081204

KEGG BRITE Database

Orthology

K13675

Name

UDP-glucose:O-linked fucose beta-1,3-glucosyltransferase [EC:2.4.1.-]

References

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0080201	Peters plus syndrome	Glyco-Disease Genes Database Alliance of Genome Resources

The Human Phenotype Ontology

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HPO ID	HPO Term
HP:0000003	Multicystic kidney dysplasia
HP:0000007	Autosomal recessive inheritance
HP:0000013	Hypoplasia of the uterus
HP:0000023	Inguinal hernia
HP:0000028	Cryptorchidism
HP:0000047	Hypospadias
HP:0000059	Hypoplastic labia majora
HP:0000060	Clitoral hypoplasia
HP:0000073	Ureteral duplication
HP:0000075	Renal duplication

Displaying **all 2** entries
Disease ID	Disease Name
OMIM:261540	Peters plus syndrome
ORPHA:709	Peters plus syndrome

PubChem Disease

GHR Health Conditions

Peters plus syndrome

MedGen Diseases

Peters plus syndrome

OMIM Phenotypes

PETERS-PLUS SYNDROME; PTRPLS

KEGG Diseases

Peters anomaly

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **31 - 40** of 61 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Chinchilla lanigera	102016185			CHILA09213
Macaca fascicularis	102136150			MACFA15298
Latimeria chalumnae	102363706			LATCH04385
Myotis lucifugus	102420622			MYOLU02887
Pelodiscus sinensis	102457631			PELSI07616
Callorhinchus milii	103177210			CALMI12521
Ursus maritimus	103664413			URSMA13507
Nannospalax galili	103727255			NANGA02901
Serinus canaria	103812552			SERCA01614
Rhinopithecus roxellana	104665323			RHIRO07177

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024