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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
growth differentiation factor 11
Summary
- Gene Symbol
-
- Gdf11
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Cytokine
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Growth factor
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9Z1W4 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| pancreas development | ||
| negative regulation of cell population proliferation | ||
| SMAD protein signal transduction |
|
|
| camera-type eye morphogenesis | ||
| type B pancreatic cell maturation |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein-containing complex | ||
| intracellular membrane-bounded organelle | ||
| nucleoplasm | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| cytokine activity | ||
| growth factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- growth/differentiation factor 11
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytokine activity |
| growth factor activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070418 | vertebral hypersegmentation and orofacial anomalies |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 127490919 | RABIT10460 | |||
| 127671199 | 10129_0:004cd1 | |||
| 128119947 | 564181_0:00262e | |||
| 129674960 | 48139_1:00006e | |||
| 130866608 | 269649_0:005008 | |||
| 131895014 | 42410_0:0046d0 |
