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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
growth differentiation factor 11
Summary
- Gene Symbol
-
- Gdf11
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Cytokine
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Growth factor
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9Z1W4 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| pancreas development | ||
| negative regulation of cell population proliferation | ||
| SMAD protein signal transduction |
|
|
| camera-type eye morphogenesis | ||
| type B pancreatic cell maturation |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein-containing complex | ||
| intracellular membrane-bounded organelle | ||
| nucleoplasm | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| cytokine activity | ||
| growth factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- growth/differentiation factor 11
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytokine activity |
| growth factor activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070418 | vertebral hypersegmentation and orofacial anomalies |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 109073012 | CYPCA123262 | |||
| 109696237 | 51338_0:000582 | |||
| 110303901 | 10089_0:002c34 | |||
| 110326395 | 10093_0:0024b9 | |||
| 110560819 | 10047_0:003764 | |||
| 112922221 | VULVU15539 | |||
| 113189509 | 9999_0:002351 | |||
| 113583801 | ELEEL32895 | |||
| 113892798 | BOBOX39330 | |||
| 114037946 | VOMUR26907 |
