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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glutamate-cysteine ligase, catalytic subunit
Summary
- Gene Symbol
-
- Gclc
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Glutathione biosynthesis
- Ligase
- Phosphoprotein
- Reference proteome
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| blood vessel diameter maintenance | ||
| cellular response to glucose stimulus |
|
|
| glutamate metabolic process | ||
| negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | ||
| negative regulation of extrinsic apoptotic signaling pathway |
GO Hierarchy
- response to activity
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| glutamate-cysteine ligase complex | ||
| cytosol | ||
| mitochondrion |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| protein-containing complex binding | ||
| glutamate binding | ||
| ADP binding | ||
| nucleotide binding |
Disease
- Disease Ontology
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 106845572 | EQUAS15989 | ||
| 116815559 | CHEAB20399 | ||
| 105304805 | PTEVA08077 | ||
| 115054985 | ECHNA11692 | ||
| 115399582 | SALFA53472 | ||
| 113478403 | ATHCN05066 | ||
| 105813804 | PROCO08754 | ||
| 853344 | SGD:S000003637 | ||
| 103736919 | NANGA18181 | ||
| 116442070 | CORMO18125 |
