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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glutamate-cysteine ligase, catalytic subunit
Summary
- Gene Symbol
-
- Gclc
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Glutathione biosynthesis
- Ligase
- Phosphoprotein
- Reference proteome
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to oxidative stress | ||
| negative regulation of apoptotic process | ||
| response to cadmium ion |
|
|
| positive regulation of proteasomal ubiquitin-dependent protein catabolic process | ||
| glutathione metabolic process |
GO Hierarchy
- response to activity
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| glutamate-cysteine ligase complex | ||
| cytosol | ||
| mitochondrion |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| catalytic activity | ||
| magnesium ion binding | ||
| ligase activity | ||
| glutamate-cysteine ligase activity | ||
| ATP binding |
Disease
- Disease Ontology
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 101610535 | JACJA12096 | ||
| 118283257 | SCOMX08184 | ||
| 117017146 | RHIFE11301 | ||
| 100218278 | TAEGU20373 | ||
| 103221339 | CHLSB06206 | ||
| 108530203 | RHIBE34626 | ||
| 104662843 | RHIRO05317 | ||
| 100607388 | NOMLE21041 | ||
| 114593824 | PODMU17854 | ||
| 107597697 | SINGR60592 |
