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glutamate receptor, ionotropic, kainate 3

Summary

Gene Symbol

Grik3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14807

PubChem

14807

Alliance of Genome Resources

MGI:95816

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Isopeptide bond
Ligand-gated ion channel
Phosphoprotein
Postsynaptic cell membrane
Receptor
Reference proteome
Signal
Transmembrane helix
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
B1AS29	Glutamate receptor 7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
negative regulation of synaptic transmission, glutamatergic	ISO
adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway	IEA
regulation of membrane potential	ISO
calcium-mediated signaling	IEA
modulation of chemical synaptic transmission	IBA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

signal transduction [inference]

cell surface receptor signaling pathway [inference]

glutamate receptor signaling pathway

G protein-coupled glutamate receptor signaling pathway

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

ionotropic glutamate receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

G protein-coupled glutamate receptor signaling pathway

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

ligand-gated ion channel signaling pathway [inference]

ionotropic glutamate receptor signaling pathway

transmembrane transport [inference]

monoatomic ion transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, glutamatergic

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, glutamatergic

regulation of synaptic transmission, glutamatergic [inference]

negative regulation of synaptic transmission, glutamatergic

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, glutamatergic

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, glutamatergic

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

glutamate receptor signaling pathway

G protein-coupled glutamate receptor signaling pathway

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

ionotropic glutamate receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

G protein-coupled glutamate receptor signaling pathway

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

ligand-gated ion channel signaling pathway [inference]

ionotropic glutamate receptor signaling pathway

regulation of cell communication [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, glutamatergic

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, glutamatergic

regulation of synaptic transmission, glutamatergic [inference]

negative regulation of synaptic transmission, glutamatergic

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, glutamatergic

regulation of biological quality [inference]

regulation of membrane potential

regulation of presynaptic membrane potential

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
dendrite cytoplasm	ISO
glutamatergic synapse	IDA IEP IMP	17620617 26448475
axon	ISO
dendrite	ISO
plasma membrane	IBA IDA ISO	15805114

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

neurotransmitter receptor complex [inference]

ionotropic glutamate receptor complex [inference]

kainate selective glutamate receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

neurotransmitter receptor complex [inference]

ionotropic glutamate receptor complex [inference]

kainate selective glutamate receptor complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

ionotropic glutamate receptor complex [inference]

kainate selective glutamate receptor complex

cation channel complex [inference]

potassium channel complex [inference]

kainate selective glutamate receptor complex

sodium channel complex [inference]

kainate selective glutamate receptor complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

ionotropic glutamate receptor complex [inference]

kainate selective glutamate receptor complex

cation channel complex [inference]

potassium channel complex [inference]

kainate selective glutamate receptor complex

sodium channel complex [inference]

kainate selective glutamate receptor complex

cellular anatomical entity [inference]

cytoplasm [inference]

cytoplasmic region [inference]

plasma membrane bounded cell projection cytoplasm [inference]

neuron projection cytoplasm [inference]

dendrite cytoplasm

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic membrane

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

perikaryon

presynapse [inference]

terminal bouton

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
glutamate-gated calcium ion channel activity	IDA	20007474
glutamate receptor activity	ISO
kainate selective glutamate receptor activity	IBA IEA ISO
ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	IDA IEP IMP	17620617
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IBA