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cystathionine gamma-lyase

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

1491

PubChem

1491

Alliance of Genome Resources

HGNC:2501

Annotation

Keyword

3D-structure
Alternative splicing
Calmodulin-binding
Cysteine biosynthesis
Cytoplasm
Disease variant
Lipid metabolism
Lyase
Pyridoxal phosphate
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P32929	Cysteine desulfhydrase Cysteine-protein sulfhydrase Gamma-cystathionase Homocysteine desulfhydrase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
cysteine metabolic process	TAS	1339280
lipid metabolic process	IEA
protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine	IDA	19019829
cysteine biosynthetic process via cystathionine	IDA	19428278
cysteine biosynthetic process via cystathionine	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sulfur amino acid metabolic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

cysteine metabolic process

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

transsulfuration

homocysteine metabolic process [inference]

transsulfuration

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

cysteine metabolic process

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

transsulfuration

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

homoserine metabolic process [inference]

transsulfuration

homocysteine metabolic process [inference]

transsulfuration

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine

protein-pyridoxal-5-phosphate linkage [inference]

protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine

protein sulfhydration

organonitrogen compound biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

sulfur compound biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

hydrogen sulfide biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

organonitrogen compound biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

sulfur amino acid metabolic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

cysteine metabolic process

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

transsulfuration

homocysteine metabolic process [inference]

transsulfuration

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

cysteine metabolic process

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

transsulfuration

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

homoserine metabolic process [inference]

transsulfuration

homocysteine metabolic process [inference]

transsulfuration

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

carboxylic acid biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

sulfur compound metabolic process [inference]

sulfur amino acid metabolic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

cysteine metabolic process

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

transsulfuration

homocysteine metabolic process [inference]

transsulfuration

sulfur compound biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

hydrogen sulfide biosynthetic process

hydrogen sulfide metabolic process [inference]

hydrogen sulfide biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

sulfur compound biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

hydrogen sulfide biosynthetic process

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

cysteine metabolic process

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

transsulfuration

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

homoserine metabolic process [inference]

transsulfuration

homocysteine metabolic process [inference]

transsulfuration

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

lipid metabolic process

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine

protein-pyridoxal-5-phosphate linkage [inference]

protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine

protein sulfhydration

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

sulfur amino acid metabolic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

cysteine metabolic process

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

transsulfuration

homocysteine metabolic process [inference]

transsulfuration

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

cysteine metabolic process

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

transsulfuration

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

homoserine metabolic process [inference]

transsulfuration

homocysteine metabolic process [inference]

transsulfuration

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

carboxylic acid biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

sulfur amino acid metabolic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

cysteine metabolic process

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

transsulfuration

homocysteine metabolic process [inference]

transsulfuration

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

cysteine metabolic process

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

transsulfuration

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

homoserine metabolic process [inference]

transsulfuration

homocysteine metabolic process [inference]

transsulfuration

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

carboxylic acid biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

lipid metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine

protein-pyridoxal-5-phosphate linkage [inference]

protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine

protein sulfhydration

macromolecule modification [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine

protein-pyridoxal-5-phosphate linkage [inference]

protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine

protein sulfhydration

organonitrogen compound metabolic process [inference]

sulfur amino acid metabolic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

cysteine metabolic process

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

transsulfuration

homocysteine metabolic process [inference]

transsulfuration

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

cysteine metabolic process

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

transsulfuration

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

homoserine metabolic process [inference]

transsulfuration

homocysteine metabolic process [inference]

transsulfuration

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine

protein-pyridoxal-5-phosphate linkage [inference]

protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine

protein sulfhydration

organonitrogen compound biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

organonitrogen compound biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

sulfur amino acid metabolic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

cysteine metabolic process

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

transsulfuration

homocysteine metabolic process [inference]

transsulfuration

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

cysteine metabolic process

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

transsulfuration

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

homoserine metabolic process [inference]

transsulfuration

homocysteine metabolic process [inference]

transsulfuration

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

carboxylic acid biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

sulfur compound metabolic process [inference]

sulfur amino acid metabolic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

cysteine metabolic process

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

transsulfuration

homocysteine metabolic process [inference]

transsulfuration

sulfur compound biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

hydrogen sulfide biosynthetic process

hydrogen sulfide metabolic process [inference]

hydrogen sulfide biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

sulfur compound biosynthetic process [inference]

sulfur amino acid biosynthetic process [inference]

cysteine biosynthetic process

cysteine biosynthetic process via cystathionine

hydrogen sulfide biosynthetic process

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

response to leukemia inhibitory factor [inference]

cellular response to leukemia inhibitory factor

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of aortic smooth muscle cell differentiation

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of aortic smooth muscle cell differentiation

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of aortic smooth muscle cell differentiation

regulation of muscle cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of aortic smooth muscle cell differentiation

regulation of smooth muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of aortic smooth muscle cell differentiation

regulation of vascular associated smooth muscle cell differentiation [inference]

regulation of aortic smooth muscle cell differentiation [inference]

positive regulation of aortic smooth muscle cell differentiation

positive regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of aortic smooth muscle cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of aortic smooth muscle cell differentiation

regulation of cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of aortic smooth muscle cell differentiation

regulation of muscle cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of aortic smooth muscle cell differentiation

regulation of smooth muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of aortic smooth muscle cell differentiation

regulation of vascular associated smooth muscle cell differentiation [inference]

regulation of aortic smooth muscle cell differentiation [inference]

positive regulation of aortic smooth muscle cell differentiation

positive regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of aortic smooth muscle cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of aortic smooth muscle cell differentiation

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytoplasm	IBA
cytosol	TAS
extracellular exosome	HDA	19056867

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

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GO Term	Evidence Code	PMID
cystathionine gamma-lyase activity	IDA	10212249 19019829 19428278
cystathionine gamma-lyase activity	IBA
protein binding	IPI	22169477 25416956 32296183
calmodulin binding	IEA
pyridoxal phosphate binding	IDA	10212249 19019829

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-sulfur lyase activity [inference]

binding [inference]

protein binding

small molecule binding [inference]

vitamin binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

heterocyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

pyridoxal phosphate binding

organic cyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

lyase

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
P: Inorganic ion transport and metabolism

Displaying **all 4** entries
Gene Ontology
carbon-sulfur lyase activity
catalytic activity
pyridoxal phosphate binding
transsulfuration

Displaying **all 4** entries
InterPro
Cys/Met metabolism, pyridoxal phosphate-dependent enzyme
Pyridoxal phosphate-dependent transferase, major domain
Pyridoxal phosphate-dependent transferase, small domain
Pyridoxal phosphate-dependent transferase

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0090142	cystathioninuria	Alliance of Genome Resources
DOID:9252	amino acid metabolic disorder	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 82 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	1491	Xenbase:XB-GENE-5784449
Rattus norvegicus	24962		RATNO24933
Mus musculus	107869	Xenbase:XB-GENE-5784449	MOUSE37158
Danio rerio	322055		DANRE37661
Pan troglodytes	456939		PANTR21371
Canis lupus familiaris	479991		CANLF17003
Bos taurus	539159		BOVIN26730
Macaca mulatta	696664		MACMU22522
Sus scrofa	733654		PIGXX30148
Equus caballus	100053614		HORSE34993

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements