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hydroxysteroid 11-beta dehydrogenase 1

Summary

Gene Symbol

Hsd11b1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

15483

PubChem

15483

Alliance of Genome Resources

MGI:103562

Annotation

Keyword

3D-structure
Endoplasmic reticulum
Glycoprotein
NADP
Oxidoreductase
Proteomics identification
Reference proteome
Signal-anchor
Steroid metabolism
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q4JHD9	7-oxosteroid reductase Corticosteroid 11-beta-dehydrogenase isozyme 1
P50172	11-beta-hydroxysteroid dehydrogenase/microsomal carbonyl reductase 11beta-HSD1A 7-oxosteroid reductase Corticosteroid 11-beta-dehydrogenase isozyme 1 liver-type 11-beta-HSD
Q3TJI8	7-oxosteroid reductase Corticosteroid 11-beta-dehydrogenase isozyme 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
glucocorticoid biosynthetic process	ISO
steroid catabolic process	IBA
glucocorticoid catabolic process	ISO
steroid metabolic process	IEA
mineralocorticoid metabolic process	ISO

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

organic substance catabolic process [inference]

lipid catabolic process [inference]

steroid catabolic process

glucocorticoid catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process

glucocorticoid catabolic process

biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

hormone metabolic process [inference]

mineralocorticoid metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

steroid catabolic process

glucocorticoid catabolic process

glucocorticoid metabolic process [inference]

mineralocorticoid metabolic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

lipid catabolic process [inference]

steroid catabolic process

glucocorticoid catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

steroid catabolic process

glucocorticoid catabolic process

glucocorticoid metabolic process [inference]

mineralocorticoid metabolic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

lipid catabolic process [inference]

steroid catabolic process

glucocorticoid catabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

steroid catabolic process

glucocorticoid catabolic process

glucocorticoid metabolic process [inference]

mineralocorticoid metabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process

glucocorticoid catabolic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

steroid catabolic process

glucocorticoid catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process

glucocorticoid catabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

glucocorticoid biosynthetic process

cellular process [inference]

mineralocorticoid metabolic process

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

lung development

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of catabolic process [inference]

regulation of carbohydrate catabolic process [inference]

regulation of pentose-phosphate shunt

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process [inference]

regulation of NADP metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of generation of precursor metabolites and energy [inference]

regulation of pentose-phosphate shunt

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process [inference]

regulation of NADP metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process [inference]

regulation of NADP metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of amide metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of small molecule metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process [inference]

regulation of NADP metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of carbohydrate catabolic process [inference]

regulation of pentose-phosphate shunt

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process [inference]

regulation of NADP metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process [inference]

regulation of NADP metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of generation of precursor metabolites and energy [inference]

regulation of pentose-phosphate shunt

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process [inference]

regulation of NADP metabolic process [inference]

regulation of pentose-phosphate shunt

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

mineralocorticoid metabolic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	ISO
endoplasmic reticulum membrane	IBA
endoplasmic reticulum membrane	IEA
nuclear membrane	ISO
intracellular membrane-bounded organelle	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

apical part of cell

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
steroid binding	ISO
steroid binding	IBA
protein homodimerization activity	ISO
protein homodimerization activity	IEA
7-beta-hydroxysteroid dehydrogenase (NADP+) activity	IEA