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cytochrome P450 family 2 subfamily B member 6
Summary
- Gene Symbol
-
- CYP2B6
- Aliases
-
- CPB6
- CYPIIB6
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Heme
- Lipid metabolism
- Membrane
- Microsome
- Monooxygenase
- NADP
- Phosphoprotein
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| P20813 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| epoxygenase P450 pathway | ||
| xenobiotic catabolic process | ||
| cellular ketone metabolic process | ||
| steroid metabolic process | ||
| xenobiotic metabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular membrane-bounded organelle | ||
| cytoplasm | ||
| endoplasmic reticulum membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| testosterone 16-alpha-hydroxylase activity |
GO Hierarchy
molecular function
catalytic activity [inference]
oxidoreductase activity [inference]
monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0014667 | disease of metabolism | |
| DOID:0050167 | autoimmune polyendocrine syndrome type 1 | |
| DOID:0050328 | congenital hypothyroidism | |
| DOID:0050426 | Stevens-Johnson syndrome | |
| DOID:0050453 | lissencephaly | |
| DOID:0050462 | Antley-Bixler syndrome with disordered steroidogenesis | |
| DOID:0050471 | Carney complex | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050590 | severe congenital neutropenia | |
| DOID:0050635 | alternating hemiplegia of childhood |
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP000449
- Gene Name
- cytochrome P450, family 2, subfamily B, polypeptide 6
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 178695 | WB:WBGene00016697 | ||
| 178704 | WB:WBGene00018413 | ||
| 178803 | WB:WBGene00019472 | ||
| 179148 | WB:WBGene00015709 | ||
| 181850 | WB:WBGene00015043 | ||
| 181851 | WB:WBGene00015044 | ||
| 181852 | WB:WBGene00015045 | ||
| 182176 | WB:WBGene00015399 | ||
| 182177 | WB:WBGene00015400 | ||
| 182888 | WB:WBGene00016092 |
