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MIRAGE
5-hydroxytryptamine (serotonin) receptor 2C
Summary
- Gene Symbol
-
- Htr2c
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Behavior
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Reference proteome
- Signal
- Synaptosome
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| behavioral fear response | ||
| intracellular calcium ion homeostasis | ||
| intracellular calcium ion homeostasis | ||
| G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | ||
| phospholipase C-activating G protein-coupled receptor signaling pathway |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| external side of plasma membrane | ||
| cell surface |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| Gq/11-coupled serotonin receptor activity | ||
| Gq/11-coupled serotonin receptor activity | ||
| G protein-coupled serotonin receptor activity | ||
| G protein-coupled serotonin receptor activity | ||
| G protein-coupled serotonin receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- 5-hydroxytryptamine receptor
- Functional Category
-
- I: Lipid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| 5-hydroxytryptamine receptor family |
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11983 | Prader-Willi syndrome | |
| DOID:9352 | type 2 diabetes mellitus |
