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MIRAGE
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Summary
- Gene Symbol
-
- Slc6a4
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Antiport
- Cell junction
- Cell membrane
- Cell projection
- Disulfide bond
- Endosome
- Glycoprotein
- Metal-binding
- Neurotransmitter transport
- Phosphoprotein
- Reference proteome
- Sodium
- Synapse
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q60857 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to hypoxia | ||
| neurotransmitter transport | ||
| serotonin transport | ||
| serotonin transport | ||
| amino acid transport |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| focal adhesion | ||
| endosome membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| integrin binding | ||
| integrin binding | ||
| monoatomic cation channel activity | ||
| monoatomic cation channel activity | ||
| neurotransmitter transmembrane transporter activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- sodium-dependent serotonin transporter
- Functional Category
-
- F: Nucleotide transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| metal ion binding |
| neurotransmitter transport |
| serotonin binding |
| serotonin uptake |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder | |
| DOID:9007 | sudden infant death syndrome |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 6532 | ZFIN:ZDB-GENE-060314-1 | HUMAN32767 | |
| 15567 | ZFIN:ZDB-GENE-060314-2 | ||
| 25553 | ZFIN:ZDB-GENE-060314-1 | RATNO02593 | |
| 37895 | ZFIN:ZDB-GENE-060314-2 | ||
| 282365 | BOVIN12451 | ||
| 443491 | SHEEP02579 | ||
| 468201 | PANTR14372 | ||
| 491184 | CANLF19117 | ||
| 574140 | MACMU13694 | ||
| 664719 | DANRE08795 |
