GlyCosmos Portal

Submissions

vacuolar protein sorting 13 homolog B

Summary

Gene Symbol

VPS13B

Organism

Homo sapiens (human)

External Links

NCBI Gene

157680

PubChem

157680

Alliance of Genome Resources

HGNC:2183

Annotation

Keyword

Alternative splicing
Cytoplasmic vesicle
Disease variant
Endosome
Golgi apparatus
Lipid transport
Lipid-binding
Lysosome
Membrane
Obesity
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7Z7G8	Cohen syndrome protein 1 Vacuolar protein sorting-associated protein 13B

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

1

2

3

4

Next ›

Last »
GO Term	Evidence Code	PMID
maintenance of lens transparency	ISS
Golgi organization	IMP	25492866
multicellular organism growth	IEA
acrosome assembly	ISS
vesicle-mediated transport	IMP	32375900

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport

endosomal transport [inference]

endocytic recycling [inference]

slow endocytic recycling

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

slow endocytic recycling

cellular process involved in reproduction in multicellular organism [inference]

acrosome assembly

cellular localization [inference]

intracellular transport [inference]

endosomal transport [inference]

endocytic recycling [inference]

slow endocytic recycling

localization within membrane [inference]

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

slow endocytic recycling

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

Golgi organization

Golgi reassembly

vesicle organization [inference]

secretory granule organization [inference]

acrosome assembly

organelle assembly [inference]

acrosome assembly

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

acrosome assembly

organelle assembly [inference]

acrosome assembly

Golgi reassembly

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development

reproductive process [inference]

developmental process involved in reproduction [inference]

acrosome assembly

cellular process involved in reproduction in multicellular organism [inference]

acrosome assembly

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

memory

behavior [inference]

learning or memory [inference]

memory

social behavior

multicellular organism growth

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

maintenance of lens transparency

developmental process [inference]

developmental process involved in reproduction [inference]

acrosome assembly

anatomical structure morphogenesis [inference]

head morphogenesis

anatomical structure formation involved in morphogenesis [inference]

cellular component assembly involved in morphogenesis [inference]

acrosome assembly

anatomical structure development [inference]

tissue development [inference]

connective tissue development [inference]

adipose tissue development

dentate gyrus development

animal organ development [inference]

muscle organ development

system development [inference]

muscle structure development [inference]

muscle organ development

growth [inference]

developmental growth [inference]

multicellular organism growth

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

maintenance of lens transparency

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

endosomal transport [inference]

endocytic recycling [inference]

slow endocytic recycling

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

slow endocytic recycling

intracellular transport [inference]

endosomal transport [inference]

endocytic recycling [inference]

slow endocytic recycling

organic substance transport [inference]

lipid transport

establishment of localization in cell [inference]

intracellular transport [inference]

endosomal transport [inference]

endocytic recycling [inference]

slow endocytic recycling

cellular localization [inference]

intracellular transport [inference]

endosomal transport [inference]

endocytic recycling [inference]

slow endocytic recycling

localization within membrane [inference]

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

slow endocytic recycling

biological process involved in intraspecies interaction between organisms [inference]

social behavior

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
endoplasmic reticulum-Golgi intermediate compartment membrane	IDA IEA	21865173
cis-Golgi network membrane	IDA	21865173
acrosomal membrane	ISS
trans-Golgi network membrane	IDA	21865173
Golgi membrane	IDA	25492866

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

secretory granule membrane [inference]

acrosomal membrane

trans-Golgi network membrane

bounding membrane of organelle [inference]

Golgi membrane

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane [inference]

secretory granule membrane [inference]

acrosomal membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
phosphatidylinositol-3-phosphate binding	ISS

GO Hierarchy

molecular function

binding [inference]

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol-3-phosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

vacuolar protein sorting-associated protein

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
lipid transport

Displaying **all 2** entries
InterPro
Intermembrane lipid transfer protein VPS13B
Vacuolar protein sorting-associated protein 13, DH-like domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0111590	Cohen syndrome	Alliance of Genome Resources
DOID:83	cataract	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 80 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	43550		FB:FBgn0039727
Rattus norvegicus	315036		RGD:1311183	RATNO38381
Canis lupus familiaris	481981			CANLF03107
Bos taurus	512656			BOVIN06129
Mus musculus	666173		MGI:1916380	MOUSE15925
Macaca mulatta	704477			MACMU43800
Pan troglodytes	740973	9598_0:0023f6
Monodelphis domestica	100023298			MONDO19739
Equus caballus	100055772			HORSE42441
Ornithorhynchus anatinus	100074626			ORNAN20756

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements