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stereocilin

Summary

Gene Symbol

STRC

Organism

Homo sapiens (human)

External Links

NCBI Gene

161497

PubChem

161497

Alliance of Genome Resources

HGNC:16035

Annotation

Keyword

Cilium
Glycoprotein
Hearing
Non-syndromic deafness
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7RTU9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cell-matrix adhesion	IBA
protein localization	IEA
detection of mechanical stimulus involved in sensory perception of sound	IEA
auditory receptor cell stereocilium organization	ISS

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion [inference]

cell-matrix adhesion

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

inner ear receptor cell stereocilium organization [inference]

auditory receptor cell stereocilium organization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

detection of mechanical stimulus involved in sensory perception of sound

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

response to mechanical stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

response to abiotic stimulus [inference]

detection of abiotic stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

response to mechanical stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

detection of stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

detection of abiotic stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

detection of stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cell surface	IBA
stereocilium tip	ISS
stereocilium tip	IBA
kinocilium	ISS
kinocilium	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

non-motile cilium [inference]

9+2 non-motile cilium [inference]

kinocilium

neuron projection [inference]

kinocilium

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

non-motile cilium [inference]

9+2 non-motile cilium [inference]

kinocilium

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Stereocilin

Functional Category

O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
cell-matrix adhesion

Displaying **all 2** entries
InterPro
Stereocilin, LRR domain
Stereocilin-related

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0110471	autosomal recessive nonsyndromic deafness 16	Alliance of Genome Resources
DOID:10003	sensorineural hearing loss	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 46 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	140476	ZFIN:ZDB-GENE-110411-215	MOUSE32525
Xenopus laevis	161497	Xenbase:XB-GENE-17338062
Bos taurus	528436		BOVIN16858
Rattus norvegicus	691937		RATNO28482
Pan troglodytes	742658		PANTR10153
Monodelphis domestica	100011646		MONDO06168
Equus caballus	100056242		HORSE16949
Callithrix jacchus	100393330		CALJA01439
Pongo abelii	100434832		PONAB08785
Pongo abelii	100436701		PONAB08785

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements