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interleukin 7 receptor

Summary

Gene Symbol

Il7r

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16197

PubChem

16197

Alliance of Genome Resources

MGI:96562

Annotation

Keyword

3D-structure
Disulfide bond
Glycoprotein
Phosphoprotein
Receptor
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P16872
Q5FW78
Q8C9W4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **21 - 23** of 23 in total

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GO Term	Evidence Code	PMID
T cell differentiation in thymus	IMP	9215626
gene expression	IMP	18958875
negative regulation of T cell apoptotic process	IMP	9215624

GO Hierarchy

biological process

immune system process [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

leukocyte mediated cytotoxicity [inference]

T cell mediated cytotoxicity

lymphocyte mediated immunity [inference]

T cell mediated immunity [inference]

T cell mediated cytotoxicity

production of molecular mediator of immune response [inference]

immunoglobulin production

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity [inference]

T cell mediated cytotoxicity

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

T cell differentiation

T cell differentiation in thymus

T cell activation [inference]

T cell differentiation

T cell differentiation in thymus

B cell activation [inference]

B cell proliferation

lymphocyte proliferation [inference]

B cell proliferation

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

production of molecular mediator of immune response [inference]

immunoglobulin production

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

production of molecular mediator of immune response [inference]

immunoglobulin production

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

production of molecular mediator of immune response [inference]

immunoglobulin production

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

production of molecular mediator of immune response [inference]

immunoglobulin production

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

production of molecular mediator of immune response [inference]

immunoglobulin production

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

T cell differentiation

T cell differentiation in thymus

T cell activation [inference]

T cell differentiation

T cell differentiation in thymus

B cell activation [inference]

B cell proliferation

lymphocyte proliferation [inference]

B cell proliferation

cell killing [inference]

leukocyte mediated cytotoxicity [inference]

T cell mediated cytotoxicity

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

interleukin-7-mediated signaling pathway

cell population proliferation [inference]

leukocyte proliferation [inference]

mononuclear cell proliferation [inference]

lymphocyte proliferation [inference]

B cell proliferation

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

production of molecular mediator of immune response [inference]

immunoglobulin production

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation

T cell differentiation in thymus

cell development [inference]

hemopoiesis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

regulation of cellular component size [inference]

regulation of cell size

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

T cell differentiation

T cell differentiation in thymus

T cell activation [inference]

T cell differentiation

T cell differentiation in thymus

B cell activation [inference]

B cell proliferation

lymphocyte proliferation [inference]

B cell proliferation

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

anatomical structure development [inference]

cell development [inference]

hemopoiesis

animal organ development [inference]

hematopoietic or lymphoid organ development [inference]

lymph node development

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation

T cell differentiation in thymus

cell development [inference]

hemopoiesis

homeostatic process [inference]

cellular homeostasis

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity [inference]

T cell mediated cytotoxicity

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of T cell activation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of immune effector process [inference]

negative regulation of immune effector process [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

regulation of leukocyte mediated immunity [inference]

regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of T cell mediated cytotoxicity

regulation of T cell mediated cytotoxicity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of leukocyte mediated immunity [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

regulation of lymphocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

regulation of T cell mediated immunity [inference]

regulation of T cell mediated cytotoxicity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

regulation of immune response [inference]

regulation of adaptive immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

regulation of T cell mediated cytotoxicity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of cellular process [inference]

negative regulation of cell killing [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of leukocyte apoptotic process [inference]

negative regulation of lymphocyte apoptotic process [inference]

negative regulation of T cell apoptotic process

negative regulation of response to stimulus [inference]

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of receptor signaling pathway via JAK-STAT

negative regulation of response to stimulus [inference]

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

regulation of immune response [inference]

regulation of adaptive immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

regulation of T cell mediated cytotoxicity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of T cell mediated immunity [inference]

negative regulation of T cell mediated cytotoxicity

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

interleukin-7-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of receptor signaling pathway via JAK-STAT

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cell killing [inference]

regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of T cell mediated cytotoxicity

regulation of T cell mediated cytotoxicity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of cell killing [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of T cell mediated cytotoxicity

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of leukocyte apoptotic process [inference]

negative regulation of lymphocyte apoptotic process [inference]

negative regulation of T cell apoptotic process

regulation of leukocyte apoptotic process [inference]

regulation of lymphocyte apoptotic process [inference]

negative regulation of lymphocyte apoptotic process [inference]

negative regulation of T cell apoptotic process

regulation of T cell apoptotic process [inference]

negative regulation of T cell apoptotic process

negative regulation of leukocyte apoptotic process [inference]

negative regulation of lymphocyte apoptotic process [inference]

negative regulation of T cell apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of leukocyte apoptotic process [inference]

negative regulation of lymphocyte apoptotic process [inference]

negative regulation of T cell apoptotic process

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

negative regulation of cellular process [inference]

negative regulation of cell killing [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of T cell mediated cytotoxicity

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of leukocyte apoptotic process [inference]

negative regulation of lymphocyte apoptotic process [inference]

negative regulation of T cell apoptotic process

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of T cell activation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of T cell activation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell activation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of T cell differentiation in thymus [inference]

positive regulation of T cell differentiation in thymus

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of T cell differentiation in thymus

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of cell size

Displaying **all 5** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IBA IDA	12714519 15294943 15909309 18958875 19934022
membrane
plasma membrane	ISO TAS
nucleoplasm	IEA ISO
cytosol	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytokine receptor activity	IBA ISO
interleukin-7 receptor activity	IEA ISO

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity

interleukin-7 receptor activity

immune receptor activity [inference]

cytokine receptor activity

interleukin-7 receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

interleukin-7 receptor subunit alpha

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cytokine-mediated signaling pathway
hemopoiesis

Displaying **all 5** entries
InterPro
Fibronectin type III superfamily
Fibronectin type III
IL-7Ralpha, fibronectin type III domain
Immunoglobulin-like fold
Short hematopoietin receptor, family 1, conserved site

Disease

Disease Ontology

Displaying **all 7** entries
DO ID	Disease Name	Source
DOID:10534	stomach cancer	Alliance of Genome Resources
DOID:219	colon cancer	Alliance of Genome Resources
DOID:3525	middle cerebral artery infarction	Alliance of Genome Resources
DOID:3908	lung non-small cell carcinoma	Alliance of Genome Resources
DOID:612	primary immunodeficiency disease	Alliance of Genome Resources
DOID:627	severe combined immunodeficiency	Alliance of Genome Resources
DOID:7474	malignant pleural mesothelioma	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 98 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Sarcophilus harrisii	100915478			SARHA05096
Pan paniscus	100981232			PANPA32139
Papio anubis	100997339			PAPAN31169
Saimiri boliviensis boliviensis	101044161			SAIBB10109
Felis catus	101100697			FELCA01365
Ovis aries	101111126			SHEEP06998
Gorilla gorilla gorilla	101140372			GORGO12935
Octodon degus	101561162	10160_0:00018c		OCTDE00953
Jaculus jaculus	101607701	51337_0:003ed0		JACJA03725
Mustela putorius furo	101686489			MUSPF19873

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Last updated: December 9, 2024