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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
integrin alpha V
Summary
- Gene Symbol
-
- Itgav
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Angiogenesis
- Calcium
- Cell adhesion
- Cell junction
- Cell membrane
- Cleavage on pair of basic residues
- Developmental protein
- Differentiation
- Disulfide bond
- Glycoprotein
- Integrin
- Metal-binding
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P43406 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| blood vessel development | ||
| positive regulation of intracellular signal transduction | ||
| substrate adhesion-dependent cell spreading |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| integrin alphav-beta5 complex | ||
| external side of plasma membrane | ||
| membrane | ||
| integrin alphav-beta8 complex | ||
| focal adhesion |
| GO Term | Evidence Code | PMID |
|---|---|---|
| transforming growth factor beta binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- integrin alpha-V
- Functional Category
-
- D: Cell cycle control, cell division, chromosome partitioning
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
| Gene Ontology |
|---|
| angiogenesis |
| cell adhesion mediated by integrin |
| cell-matrix adhesion |
| integrin binding |
| integrin-mediated signaling pathway |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1059 | intellectual disability | |
| DOID:10763 | hypertension | |
| DOID:11382 | corneal neovascularization | |
| DOID:326 | ischemia | |
| DOID:4195 | hyperglycemia | |
| DOID:4248 | coronary stenosis | |
| DOID:7693 | abdominal aortic aneurysm | |
| DOID:9119 | acute myeloid leukemia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100604485 | NOMLE21569 | |||
| 100671252 | LOXAF18873 | |||
| 100697617 | ORENI21256 | |||
| 100728575 | 10141_0:004763 | CAVPO01930 | ||
| 100752313 | 10029_0:003e62 | CRIGR11278 | ||
| 100929053 | SARHA04240 | |||
| 100975589 | PANPA26237 | |||
| 101017655 | PAPAN02094 | |||
| 101032614 | SAIBB39356 | |||
| 101085820 | FELCA18567 |
