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integrin beta 5

Summary

Gene Symbol

Itgb5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16419

PubChem

16419

Alliance of Genome Resources

MGI:96614

Annotation

Keyword

Alternative splicing
Calcium
Cell adhesion
Cell membrane
Disulfide bond
EGF-like domain
Glycoprotein
Integrin
Magnesium
Metal-binding
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
G5E8F8
O70309
Q6PE70

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
transforming growth factor beta receptor signaling pathway	IBA IMP ISO	24036928
cell migration	IBA ISO
cell adhesion
wound healing, spreading of epidermal cells	NAS	19693543
integrin-mediated signaling pathway	IBA IMP ISO NAS	19693543 24036928

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell-substrate adhesion [inference]

cell-matrix adhesion

cell adhesion mediated by integrin

cell-cell adhesion

epithelial cell-cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

integrin-mediated signaling pathway

actin filament-based process [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

stress fiber assembly

cellular developmental process [inference]

cell differentiation [inference]

endodermal cell differentiation

cell motility [inference]

cell migration

wound healing, spreading of cells [inference]

wound healing, spreading of epidermal cells

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

stress fiber assembly

cellular component assembly [inference]

actin filament bundle assembly [inference]

contractile actin filament bundle assembly [inference]

stress fiber assembly

supramolecular fiber organization [inference]

actin filament organization [inference]

actin filament bundle organization [inference]

actin filament bundle assembly [inference]

contractile actin filament bundle assembly [inference]

stress fiber assembly

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

endodermal cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

integrin-mediated signaling pathway

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
integrin complex	IBA
cell surface	IBA ISO
synaptic membrane	IDA IEP	16467530
glutamatergic synapse	IDA IEP	16467530

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alphav-beta5 complex

protein complex involved in cell adhesion [inference]

integrin complex

integrin alphav-beta5 complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alphav-beta5 complex

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

cell leading edge

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	24997346
integrin binding	IBA IPI	20826760 8601592
signaling receptor binding
metal ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding

integrin binding

cell adhesion molecule binding [inference]

integrin binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

integrin beta-5

Functional Category

E: Amino acid transport and metabolism
L: Replication, recombination and repair

Displaying **all 5** entries
Gene Ontology
cell adhesion mediated by integrin
cell migration
cell-matrix adhesion
integrin binding
integrin-mediated signaling pathway

Displaying **all 8** entries
InterPro
Integrin beta N-terminal
Integrin beta subunit, VWA domain
Integrin beta subunit, tail
Integrin beta subunit
Integrin beta tail domain superfamily
Integrin beta, epidermal growth factor-like domain 1
Integrin domain superfamily
von Willebrand factor A-like domain superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:162	cancer	Alliance of Genome Resources

Ortholog

Displaying entries **51 - 60** of **103** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Dipodomys ordii	105987905	10020_0:0020a4
Salmo salar	106582337		SALSA79316
Equus asinus asinus	106847529		EQUAS17415
Marmota marmota marmota	107143103	9994_0:0049bc
Sinocyclocheilus grahami	107555040		SINGR62467
Sinocyclocheilus grahami	107555348		SINGR77613
Rhinopithecus bieti	108517420		RHIBE16373
Castor canadensis	109698685	51338_0:000646
Phascolarctos cinereus	110208137		PHACI14701
Mus caroli	110311493	10089_0:004365

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements