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integrin beta 5

Summary

Gene Symbol

Itgb5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16419

PubChem

16419

Alliance of Genome Resources

MGI:96614

Annotation

Keyword

Alternative splicing
Calcium
Cell adhesion
Cell membrane
Disulfide bond
EGF-like domain
Glycoprotein
Integrin
Magnesium
Metal-binding
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
G5E8F8
O70309
Q6PE70

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
cell-matrix adhesion	IBA ISO NAS	19693543
cell-cell adhesion	IBA
endodermal cell differentiation
stress fiber assembly	IBA IMP ISO	24036928
cell adhesion mediated by integrin	IBA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell-substrate adhesion [inference]

cell-matrix adhesion

cell adhesion mediated by integrin

cell-cell adhesion

epithelial cell-cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

integrin-mediated signaling pathway

actin filament-based process [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

stress fiber assembly

cellular developmental process [inference]

cell differentiation [inference]

endodermal cell differentiation

cell motility [inference]

cell migration

wound healing, spreading of cells [inference]

wound healing, spreading of epidermal cells

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

stress fiber assembly

cellular component assembly [inference]

actin filament bundle assembly [inference]

contractile actin filament bundle assembly [inference]

stress fiber assembly

supramolecular fiber organization [inference]

actin filament organization [inference]

actin filament bundle organization [inference]

actin filament bundle assembly [inference]

contractile actin filament bundle assembly [inference]

stress fiber assembly

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

endodermal cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

integrin-mediated signaling pathway

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
integrin complex	IBA
cell surface	IBA ISO
synaptic membrane	IDA IEP	16467530
glutamatergic synapse	IDA IEP	16467530

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alphav-beta5 complex

protein complex involved in cell adhesion [inference]

integrin complex

integrin alphav-beta5 complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alphav-beta5 complex

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

cell leading edge

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	24997346
integrin binding	IBA IPI	20826760 8601592
signaling receptor binding
metal ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding

integrin binding

cell adhesion molecule binding [inference]

integrin binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

integrin beta-5

Functional Category

E: Amino acid transport and metabolism
L: Replication, recombination and repair

Displaying **all 5** entries
Gene Ontology
cell adhesion mediated by integrin
cell migration
cell-matrix adhesion
integrin binding
integrin-mediated signaling pathway

Displaying **all 8** entries
InterPro
Integrin beta N-terminal
Integrin beta subunit, VWA domain
Integrin beta subunit, tail
Integrin beta subunit
Integrin beta tail domain superfamily
Integrin beta, epidermal growth factor-like domain 1
Integrin domain superfamily
von Willebrand factor A-like domain superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:162	cancer	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Grammomys surdaster	114608299	491861_0:003f7a
Peromyscus leucopus	114704849	10041_0:003135
Echeneis naucrates	115061776		ECHNA13569
Salmo trutta	115155594		SALTR11093
Salmo trutta	115160928		SALTR15368
Salarias fasciatus	115402670		SALFA50127
Gadus morhua	115533256		GADMO31378
Sparus aurata	115588070		SPAAU29688
Strigops habroptila	115608838		STRHB04105
Mastomys coucha	116085844	35658_0:0007be

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements