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potassium large conductance calcium-activated channel, subfamily M, alpha member 1

Summary

Gene Symbol

Kcnma1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16531

PubChem

16531

Alliance of Genome Resources

MGI:99923

Annotation

Keyword

Alternative splicing
Calcium
Cell membrane
Magnesium
Metal-binding
Palmitate
Phosphoprotein
Potassium channel
Proteomics identification
Reference proteome
Transmembrane helix
Voltage-gated channel

Proteins

Displaying **all 7** entries
UniProt	Protein Name
Q08460	BK channel BKCA alpha Calcium-activated potassium channel, subfamily M subunit alpha-1 K(VCA)alpha KCa1.1 Maxi K channel Slo-alpha Slo1 Slowpoke homolog
A0A087WRS4	BK channel BKCA alpha Calcium-activated potassium channel, subfamily M subunit alpha-1 K(VCA)alpha KCa1.1 Maxi K channel Slo-alpha Slo1 Slowpoke homolog
A0A087WQ41	BK channel BKCA alpha Calcium-activated potassium channel, subfamily M subunit alpha-1 K(VCA)alpha KCa1.1 Maxi K channel Slo-alpha Slo1 Slowpoke homolog
A0A087WQN5	BK channel BKCA alpha Calcium-activated potassium channel, subfamily M subunit alpha-1 K(VCA)alpha KCa1.1 Maxi K channel Slo-alpha Slo1 Slowpoke homolog
A0A286YDM6	BK channel BKCA alpha Calcium-activated potassium channel, subfamily M subunit alpha-1 K(VCA)alpha KCa1.1 Maxi K channel Slo-alpha Slo1 Slowpoke homolog
A0A286YD35	BK channel BKCA alpha Calcium-activated potassium channel, subfamily M subunit alpha-1 K(VCA)alpha KCa1.1 Maxi K channel Slo-alpha Slo1 Slowpoke homolog
Q3UXG3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 43 in total

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GO Term	Evidence Code	PMID
response to hypoxia	ISO
response to hypoxia	IDA	16306267
columnar/cuboidal epithelial cell maturation	IMP	15328414
potassium ion transport	ISO
potassium ion transport	IDA	10517674 7687074

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

mechanoreceptor differentiation [inference]

inner ear receptor cell differentiation [inference]

inner ear auditory receptor cell differentiation

epithelial cell differentiation [inference]

epidermal cell differentiation [inference]

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

cell maturation [inference]

epithelial cell maturation [inference]

columnar/cuboidal epithelial cell maturation

neuron maturation

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

regulation of cellular component size [inference]

regulation of cell size [inference]

cell volume homeostasis [inference]

negative regulation of cell volume

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

smooth muscle contraction [inference]

urinary tract smooth muscle contraction [inference]

urinary bladder smooth muscle contraction [inference]

smooth muscle contraction involved in micturition

relaxation of muscle [inference]

relaxation of smooth muscle [inference]

relaxation of vascular associated smooth muscle

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance

vasodilation

renal system process [inference]

micturition

excretion [inference]

micturition

digestive system process [inference]

saliva secretion

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

neuromuscular process [inference]

neuromuscular process controlling balance

behavior [inference]

rhythmic behavior [inference]

circadian behavior [inference]

locomotor rhythm

locomotory behavior [inference]

adult locomotory behavior [inference]

adult walking behavior

locomotor rhythm

walking behavior [inference]

adult walking behavior

adult behavior [inference]

adult locomotory behavior [inference]

adult walking behavior

secretion by tissue [inference]

saliva secretion

developmental process [inference]

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

epithelial cell maturation [inference]

columnar/cuboidal epithelial cell maturation

neuron maturation

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

mechanoreceptor differentiation [inference]

inner ear receptor cell differentiation [inference]

inner ear auditory receptor cell differentiation

epithelial cell differentiation [inference]

epidermal cell differentiation [inference]

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

cell maturation [inference]

epithelial cell maturation [inference]

columnar/cuboidal epithelial cell maturation

neuron maturation

homeostatic process [inference]

cellular homeostasis [inference]

cell volume homeostasis [inference]

negative regulation of cell volume

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular potassium ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular potassium ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular potassium ion homeostasis

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular potassium ion homeostasis

inorganic ion homeostasis [inference]

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

rhythmic process [inference]

circadian rhythm

circadian behavior [inference]

locomotor rhythm

response to stimulus [inference]

response to stress [inference]

response to external stimulus [inference]

reflex [inference]

eye blink reflex

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

response to endogenous stimulus [inference]

response to hormone [inference]

response to estrogen

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to estrogen

response to inorganic substance [inference]

response to metal ion [inference]

response to calcium ion

response to oxygen-containing compound [inference]

response to salt [inference]

response to calcium ion

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport

potassium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

secretion [inference]

body fluid secretion [inference]

saliva secretion

secretion by tissue [inference]

saliva secretion

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of aldosterone metabolic process

regulation of hormone metabolic process [inference]

regulation of aldosterone metabolic process

regulation of small molecule metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of aldosterone metabolic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of steroid metabolic process [inference]

regulation of aldosterone metabolic process

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of neuron apoptotic process

negative regulation of biological process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of muscle contraction [inference]

negative regulation of smooth muscle contraction [inference]

relaxation of vascular associated smooth muscle

negative regulation of gastro-intestinal system smooth muscle contraction [inference]

negative regulation of small intestine smooth muscle contraction

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of aldosterone metabolic process

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

positive regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

positive regulation of neuron apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of neuron apoptotic process

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of neuron apoptotic process

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle contraction [inference]

regulation of smooth muscle contraction [inference]

negative regulation of smooth muscle contraction [inference]

relaxation of vascular associated smooth muscle

negative regulation of gastro-intestinal system smooth muscle contraction [inference]

negative regulation of small intestine smooth muscle contraction

regulation of gastro-intestinal system smooth muscle contraction [inference]

negative regulation of gastro-intestinal system smooth muscle contraction [inference]

negative regulation of small intestine smooth muscle contraction

regulation of small intestine smooth muscle contraction [inference]

negative regulation of small intestine smooth muscle contraction

negative regulation of muscle contraction [inference]

negative regulation of smooth muscle contraction [inference]

relaxation of vascular associated smooth muscle

negative regulation of gastro-intestinal system smooth muscle contraction [inference]

negative regulation of small intestine smooth muscle contraction

negative regulation of multicellular organismal process [inference]

negative regulation of muscle contraction [inference]

negative regulation of smooth muscle contraction [inference]

relaxation of vascular associated smooth muscle

negative regulation of gastro-intestinal system smooth muscle contraction [inference]

negative regulation of small intestine smooth muscle contraction

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone metabolic process [inference]

regulation of aldosterone metabolic process

regulation of membrane potential

action potential [inference]

neuronal action potential

regulation of body fluid levels [inference]

body fluid secretion [inference]

saliva secretion

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of cell size [inference]

cell volume homeostasis [inference]

negative regulation of cell volume

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance

vasodilation

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum	IDA	17303127
plasma membrane	TAS
plasma membrane	IDA	10517674 12952984
caveola	ISO
voltage-gated potassium channel complex	ISO

GO Hierarchy

cellular component

protein-containing complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated potassium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

cellular anatomical entity [inference]

cytoplasm [inference]

sarcoplasm

membrane

plasma membrane

plasma membrane region [inference]

apical plasma membrane

plasma membrane raft [inference]

caveola

synaptic membrane [inference]

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

cell junction [inference]

synapse [inference]

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

cell body [inference]

neuronal cell body

perinuclear region of cytoplasm

side of membrane [inference]

external side of plasma membrane

presynapse [inference]

terminal bouton

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
actin binding	ISO
voltage-gated potassium channel activity	ISO
voltage-gated potassium channel activity	TAS
voltage-gated potassium channel activity	IDA	7687074
voltage-gated potassium channel activity	IMP	15184377