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mannosidase 2, alpha B1

Summary

Gene Symbol

Man2b1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

17159

PubChem

17159

Alliance of Genome Resources

MGI:107286

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosidase
Lysosome
Metal-binding
Reference proteome
Signal
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
O09159	Lysosomal acid alpha-mannosidase Mannosidase alpha class 2B member 1 Mannosidase alpha-B

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
mannose metabolic process	IDA	9305783 9355733
mannose metabolic process	IMP	10400983
learning or memory	IMP	16014715
oligosaccharide catabolic process	IDA	9305783
protein modification process	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process

catabolic process [inference]

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

mannose metabolic process

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

protein metabolic process [inference]

protein modification process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

mannose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

mannose metabolic process

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process

macromolecule modification [inference]

protein modification process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory

behavior [inference]

learning or memory

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GO Term	Evidence Code	PMID
extracellular space	ISO
extracellular space	IEA
nucleoplasm	ISO
nucleoplasm	IEA
lysosome	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

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GO Term	Evidence Code	PMID
alpha-mannosidase activity	ISO
alpha-mannosidase activity	IDA	9305783 9355733
alpha-mannosidase activity	IMP	10400983
alpha-mannosidase activity	IBA
mannose binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

mannosidase activity [inference]

alpha-mannosidase activity

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

mannose binding

small molecule binding [inference]

monosaccharide binding [inference]

mannose binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3413	alpha-mannosidosis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 69 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	4125	Xenbase:XB-GENE-958698	HUMAN41080
Xenopus tropicalis	17159	Xenbase:XB-GENE-958698
Xenopus tropicalis	34437	Xenbase:XB-GENE-958698
Xenopus tropicalis	180749	Xenbase:XB-GENE-958698
Bos taurus	282272		BOVIN32520
Rattus norvegicus	361378		RATNO14832
Pan troglodytes	455745		PANTR17293
Canis lupus familiaris	484932		CANLF07819
Felis catus	493697		FELCA03210
Danio rerio	541519		DANRE01910

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