GlyCosmos Portal

Submissions

Glutamate receptor ionotropic, kainate glr-3

Summary

Gene Symbol

glr-3

Organism

Caenorhabditis elegans

External Links

NCBI Gene

172449

PubChem

172449

Alliance of Genome Resources

WB:WBGene00001614

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Ligand-gated ion channel
Postsynaptic cell membrane
Receptor
Reference proteome
Sensory transduction
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q21415

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
regulation of postsynaptic membrane potential	IEA
response to stimulus	IEA
ion transmembrane transport	IEA
detection of cold stimulus involved in thermoception	IDA	31474366
detection of temperature stimulus involved in sensory perception of pain	IMP	31474366

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

transmembrane transport [inference]

monoatomic ion transmembrane transport

response to stimulus

response to external stimulus [inference]

detection of external stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception [inference]

detection of cold stimulus involved in thermoception

detection of temperature stimulus involved in sensory perception of pain

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception [inference]

detection of cold stimulus involved in thermoception

detection of temperature stimulus involved in sensory perception of pain

detection of abiotic stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception [inference]

detection of cold stimulus involved in thermoception

detection of temperature stimulus involved in sensory perception of pain

detection of stimulus [inference]

detection of external stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception [inference]

detection of cold stimulus involved in thermoception

detection of temperature stimulus involved in sensory perception of pain

detection of abiotic stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception [inference]

detection of cold stimulus involved in thermoception

detection of temperature stimulus involved in sensory perception of pain

detection of stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception [inference]

detection of cold stimulus involved in thermoception

detection of temperature stimulus involved in sensory perception of pain

detection of stimulus involved in sensory perception of pain [inference]

detection of temperature stimulus involved in sensory perception of pain

localization [inference]

establishment of localization [inference]

transport [inference]

ion transport

monoatomic ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of biological quality [inference]

regulation of membrane potential [inference]

regulation of postsynaptic membrane potential

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane	IEA
postsynaptic membrane	IEA
postsynaptic density membrane	IBA
plasma membrane	IBA IEA
synapse	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
ligand-gated monoatomic ion channel activity	IEA
glutamate receptor activity	IBA
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IBA
signaling receptor activity	IEA
ion channel activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

ion channel activity

ligand-gated monoatomic ion channel activity

extracellular ligand-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

passive transmembrane transporter activity [inference]

channel activity [inference]

ion channel activity

ligand-gated monoatomic ion channel activity

extracellular ligand-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity

extracellular ligand-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

transmitter-gated channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity [inference]

glutamate receptor activity

neurotransmitter receptor activity [inference]

transmitter-gated channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

postsynaptic neurotransmitter receptor activity [inference]

neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Receptor

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
ligand-gated monoatomic ion channel activity
monoatomic ion transport

Displaying **all 2** entries
InterPro
Periplasmic binding protein-like I
Receptor, ligand binding region

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:11832	visual epilepsy	Alliance of Genome Resources
DOID:1824	status epilepticus	Alliance of Genome Resources
DOID:3083	chronic obstructive pulmonary disease	Alliance of Genome Resources
DOID:3328	temporal lobe epilepsy	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 27 in total

1

2

3

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	2899	HGNC:4581
Homo sapiens	2900	HGNC:4582
Homo sapiens	2901	HGNC:4583
Mus musculus	14805	MGI:95814
Mus musculus	14807	MGI:95816
Mus musculus	14809	MGI:95818
Rattus norvegicus	24406	RGD:2734
Rattus norvegicus	24407	RGD:2735
Rattus norvegicus	29559	RGD:2732
Drosophila melanogaster	43806	FB:FBgn0039916