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Nicastrin
Summary
- Gene Symbol
-
- aph-2
- Organism
- Caenorhabditis elegans
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell fate commitment involved in pattern specification | ||
| Notch signaling pathway | ||
| pharynx development | ||
| egg-laying behavior | ||
| embryonic morphogenesis |
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| plasma membrane | ||
| gamma-secretase complex |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- alpha,alpha-trehalose-phosphate synthase
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- H: Coenzyme transport and metabolism
| Gene Ontology |
|---|
| catalytic activity |
| trehalose biosynthetic process |
| trehalose metabolic process |
| trehalose metabolism in response to stress |
| trehalose-phosphatase activity |
| InterPro |
|---|
| Glycosyl transferase, family 20 |
| HAD superfamily |
| HAD-like superfamily |
| Trehalose-phosphatase |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10652 | Alzheimer's disease | |
| DOID:11054 | urinary bladder cancer | |
| DOID:2280 | hidradenitis suppurativa | |
| DOID:5419 | schizophrenia | |
| DOID:8552 | chronic myeloid leukemia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 23385 | HGNC:17091 | |||
| 42964 | FB:FBgn0039234 | |||
| 59287 | MGI:1891700 | |||
| 289231 | RGD:631418 | |||
| 6096390 | 6279_0:0000e7 | |||
| 6101936 | 6279_0:00219e | |||
| 9945906 | 7209_0:001f02 | |||
| 25346333 | 51031_0:000670 | |||
| 25346334 | 51031_0:000654 | |||
| 36376867 | 34506_0:000dd9 |
