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Protein Wnt-1

Summary

Gene Symbol

cwn-1

Organism

Caenorhabditis elegans

External Links

NCBI Gene

173399

PubChem

173399

Alliance of Genome Resources

WB:WBGene00000857

Annotation

Keyword

Cell membrane
Cytoplasm
Developmental protein
Disulfide bond
Extracellular matrix
Glycoprotein
Lipoprotein
Neurogenesis
Reference proteome
Signal
Wnt signaling pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
P34888

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
cell fate specification	IGI	19389360
positive regulation of anterior/posterior axon guidance	IGI	16516839
neuron differentiation	IBA
motor neuron migration	IGI IMP	18622031
positive regulation of motor neuron migration	IGI	16516839

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

canonical Wnt signaling pathway

cellular developmental process [inference]

cell fate specification

cell differentiation [inference]

neurogenesis [inference]

generation of neurons

neuron differentiation

cell fate commitment

cell motility [inference]

cell migration [inference]

neuron migration

neuroblast migration

multicellular organismal process [inference]

multicellular organism development

developmental process [inference]

anatomical structure development [inference]

multicellular organism development

system development [inference]

nervous system development

cellular developmental process [inference]

cell fate specification

cell differentiation [inference]

neurogenesis [inference]

generation of neurons

neuron differentiation

cell fate commitment

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

regulation of chemotaxis [inference]

regulation of axon guidance [inference]

positive regulation of axon guidance [inference]

regulation of anterior/posterior axon guidance [inference]

positive regulation of anterior/posterior axon guidance

regulation of sensory neuron axon guidance [inference]

positive regulation of sensory neuron axon guidance

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

regulation of neuron migration [inference]

regulation of motor neuron migration [inference]

positive regulation of motor neuron migration

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of chemotaxis [inference]

regulation of axon guidance [inference]

positive regulation of axon guidance [inference]

regulation of anterior/posterior axon guidance [inference]

positive regulation of anterior/posterior axon guidance

regulation of sensory neuron axon guidance [inference]

positive regulation of sensory neuron axon guidance

regulation of developmental process [inference]

regulation of vulval development

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

canonical Wnt signaling pathway

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance [inference]

regulation of axon guidance [inference]

positive regulation of axon guidance [inference]

regulation of anterior/posterior axon guidance [inference]

positive regulation of anterior/posterior axon guidance

regulation of sensory neuron axon guidance [inference]

positive regulation of sensory neuron axon guidance

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

regulation of neuron migration [inference]

regulation of motor neuron migration [inference]

positive regulation of motor neuron migration

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytoplasm	IEA
plasma membrane	IEA
extracellular space	IBA
extracellular region	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytokine activity	IBA
receptor tyrosine kinase binding	IPI	17942487
signaling receptor binding	IEA
receptor ligand activity	ISS	8510930
frizzled binding	IBA ISS	7553861

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding

G protein-coupled receptor binding [inference]

frizzled binding

receptor tyrosine kinase binding

receptor ligand activity

cytokine activity

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding [inference]

receptor tyrosine kinase binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:0111526	Mullerian aplasia and hyperandrogenism	Alliance of Genome Resources
DOID:11832	visual epilepsy	Alliance of Genome Resources
DOID:1459	hypothyroidism	Alliance of Genome Resources
DOID:2871	endometrial carcinoma	Alliance of Genome Resources
DOID:3021	acute kidney failure	Alliance of Genome Resources
DOID:9970	obesity	Alliance of Genome Resources