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Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase

Summary

Gene Symbol

ptp-3

Organism

Caenorhabditis elegans

External Links

NCBI Gene

174685

PubChem

174685

Alliance of Genome Resources

WB:WBGene00004215

Annotation

Keyword

Alternative splicing
Cell junction
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Protein phosphatase
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane
Transmembrane helix

Proteins

Displaying **all 8** entries
UniProt	Protein Name
L8E6W1
G5EE54
L8E6H9
L8E7X5
L8E6L2
Q9BMN8	Protein-tyrosine phosphate 3
L8E6Z3
Q8I120

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
embryonic body morphogenesis	IMP	11959824
protein dephosphorylation	IEA ISS
synaptic membrane adhesion	IBA
signal transduction	IBA
protein localization to synapse	IMP	16107639

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

synaptic membrane adhesion

signal transduction

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

cell motility [inference]

cell migration [inference]

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to cell junction [inference]

protein localization to synapse

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance [inference]

motor neuron axon guidance

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly

synapse organization [inference]

synapse assembly

developmental process [inference]

anatomical structure morphogenesis [inference]

body morphogenesis [inference]

embryonic body morphogenesis

embryonic morphogenesis [inference]

anatomical structure development [inference]

tissue development [inference]

epidermis development

system development [inference]

nervous system development

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to cell junction [inference]

protein localization to synapse

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to cell junction [inference]

protein localization to synapse

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

Displaying **all 5** entries
GO Term	Evidence Code	PMID
adherens junction	IDA IEA IMP	11959824
synapse	IDA	16107639
plasma membrane	IEA
membrane	IEA
anchoring junction	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

cell junction [inference]

synapse

anchoring junction

cell-cell junction [inference]

adherens junction

Displaying **all 4** entries
GO Term	Evidence Code	PMID
phosphatase activity	IEA
phosphoprotein phosphatase activity	IEA
protein tyrosine phosphatase activity	IBA IDA IEA ISS	32513699
transmembrane receptor protein tyrosine phosphatase activity	ISS	11959824

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity

phosphoprotein phosphatase activity

protein tyrosine phosphatase activity

transmembrane receptor protein tyrosine phosphatase activity

transmembrane receptor protein phosphatase activity [inference]

transmembrane receptor protein tyrosine phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity

protein tyrosine phosphatase activity

transmembrane receptor protein tyrosine phosphatase activity

transmembrane receptor protein phosphatase activity [inference]

transmembrane receptor protein tyrosine phosphatase activity

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein phosphatase activity [inference]

transmembrane receptor protein tyrosine phosphatase activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
synaptic vesicle	PMID:33147118
adherens junction	PMID:11959824
synapse	PMID:16107639

Disease

Disease Ontology

Displaying **all 8** entries
DO ID	Disease Name	Source
DOID:0050425	restless legs syndrome	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:14227	azoospermia	Alliance of Genome Resources
DOID:2018	hyperinsulinism	Alliance of Genome Resources
DOID:3393	coronary artery disease	Alliance of Genome Resources
DOID:9351	diabetes mellitus	Alliance of Genome Resources
DOID:9352	type 2 diabetes mellitus	Alliance of Genome Resources
DOID:9970	obesity	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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External Links

Annotation

International Collaboration

Acknowledgements