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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Matrix metalloproteinase-A
Summary
- Gene Symbol
-
- zmp-1
- Organism
- Caenorhabditis elegans
Annotation
- Keyword
-
- Cell membrane
- Cleavage on pair of basic residues
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| G5EGM1 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| collagen catabolic process | ||
| extracellular matrix organization | ||
| basement membrane disassembly |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular matrix | ||
| plasma membrane | ||
| cell surface | ||
| basolateral plasma membrane | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| zinc ion binding | ||
| metal ion binding | ||
| metalloendopeptidase activity | ||
| metallopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- metallopeptidase
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| collagen catabolic process |
| extracellular matrix organization |
| hydrolase activity |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| zinc ion binding |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10283 | prostate cancer | |
| DOID:2671 | transitional cell carcinoma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 4324 | HGNC:7161 | |||
| 10893 | HGNC:7172 | |||
| 17385 | MGI:97008 | |||
| 17388 | MGI:109320 | |||
| 23948 | MGI:1346076 | |||
| 240047 | MGI:2443938 | |||
| 288626 | RGD:1311541 | |||
| 291848 | RGD:1308937 | |||
| 548675 | Xenbase:XB-GENE-1014388 | |||
| 548746 | Xenbase:XB-GENE-1007177 |
