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dynamin 1

Summary

Gene Symbol

DNM1

Organism

Homo sapiens (human)

External Links

NCBI Gene

1759

HGNC

2972

PubChem

1759

Alliance of Genome Resources

HGNC:2972

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Cell projection
Coated pit
Cytoplasmic vesicle
Disease variant
Endocytosis
Epilepsy
GTP-binding
Hydrolase
Methylation
Microtubule
Motor protein
Nitration
Phosphoprotein
Reference proteome
Synapse

Proteins

Displaying **all 3** entries
UniProt	Protein Name
B4DK06
Q05193	Dynamin Dynamin I
B7ZAC0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
vesicle scission	IDA	19084269
endocytosis	IMP TAS	16648839 19706678
regulation of vesicle size	ISS
receptor internalization	IBA
endosome organization	IMP	19706678

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis

receptor-mediated endocytosis

receptor internalization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

vesicle budding from membrane [inference]

synaptic vesicle budding [inference]

synaptic vesicle budding from presynaptic endocytic zone membrane

endosome organization

cellular component assembly [inference]

protein-containing complex assembly [inference]

clathrin coat assembly [inference]

clathrin coat assembly involved in endocytosis

protein complex oligomerization [inference]

protein homooligomerization

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

regulation of cellular component size [inference]

regulation of vesicle size

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

clathrin coat assembly [inference]

clathrin coat assembly involved in endocytosis

protein complex oligomerization [inference]

protein homooligomerization

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

membrane organization [inference]

vesicle budding from membrane [inference]

synaptic vesicle budding [inference]

synaptic vesicle budding from presynaptic endocytic zone membrane

membrane fission [inference]

vesicle scission

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis

receptor-mediated endocytosis

receptor internalization

import into cell [inference]

endocytosis

receptor-mediated endocytosis

receptor internalization

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of vesicle size

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
microtubule	IBA
endocytic vesicle	ISS
presynapse	ISS
chromaffin granule	IEA
presynaptic endocytic zone membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

membrane coat

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

clathrin-coated pit

synaptic membrane [inference]

presynaptic endocytic zone membrane

cell junction [inference]

synapse

ribbon synapse [inference]

photoreceptor ribbon synapse

glutamatergic synapse

cell projection

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle

secretory vesicle [inference]

secretory granule [inference]

chromaffin granule

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle

secretory vesicle [inference]

secretory granule [inference]

chromaffin granule

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle

secretory vesicle [inference]

secretory granule [inference]

chromaffin granule

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

presynapse

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	10206341 12791276 15252009 15703209 16234328 16432212 17474147 17500595 18353773 20935625 21706016 21900206 24282027 29949766 31980649 33961781 35271311 37871017 9922133
GTPase activity	IBA IDA	20428113
GDP binding	ISS
phosphatidylinositol-4,5-bisphosphate binding	IDA IMP	10074457 9765310
identical protein binding	IPI	20428113 20700106 21927000 21962517 26302298 30069048