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MIRAGE
Acetylcholine receptor subunit beta-type lev-1

Summary
Gene Symbol
  • lev-1
Organism
Caenorhabditis elegans
NCBI Gene
178269
PubChem
178269
Alliance of Genome Resources
Annotation
Keyword
  • Cell membrane
  • Disulfide bond
  • Glycoprotein
  • Ligand-gated ion channel
  • Postsynaptic cell membrane
  • Receptor
  • Reference proteome
  • Signal
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
C6KRN0
Q27218
  • Levamisole-resistant protein 1
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 13 in total
GO Term Evidence Code PMID
regulation of egg-laying behavior
monoatomic ion transport
regulation of membrane potential
synaptic transmission, cholinergic
chemical synaptic transmission
GO Hierarchy
Displaying entries 1 - 5 of 8 in total
GO Term Evidence Code PMID
acetylcholine-gated monoatomic cation-selective channel activity
extracellular ligand-gated monoatomic ion channel activity
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
acetylcholine receptor activity
transmembrane signaling receptor activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
AcetylCholine Receptor
Functional Category
  • E: Amino acid transport and metabolism
  • T: Signal transduction mechanisms
  • X: Mobilome: prophages, transposons
Displaying all 5 entries
Gene Ontology
excitatory postsynaptic potential
extracellular ligand-gated monoatomic ion channel activity
monoatomic ion channel activity
monoatomic ion transport
regulation of postsynaptic membrane potential
Displaying all 8 entries
InterPro
Neuronal acetylcholine receptor
Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Neurotransmitter-gated ion-channel ligand-binding domain
Neurotransmitter-gated ion-channel transmembrane domain superfamily
Neurotransmitter-gated ion-channel transmembrane domain
Neurotransmitter-gated ion-channel, conserved site
Neurotransmitter-gated ion-channel
Nicotinic acetylcholine receptor
Alliance of Genome Resources
Expression
Displaying all 3 entries
Location References
Disease
Disease Ontology
Displaying entries 1 - 10 of 14 in total
DO ID Disease Name Source
DOID:0050741 alcohol dependence
DOID:0050742 nicotine dependence
DOID:0110662 congenital myasthenic syndrome 1B
DOID:0110663 congenital myasthenic syndrome 1A
DOID:10534 stomach cancer
DOID:1324 lung cancer
DOID:1574 alcohol use disorder
DOID:3083 chronic obstructive pulmonary disease
DOID:3905 lung carcinoma
DOID:3908 lung non-small cell carcinoma
Ortholog
Displaying entries 1 - 10 of 15 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
1134 HGNC:1955
1136 HGNC:1957
8973 HGNC:15963
38545 FB:FBgn0000038
6102065 6279_0:00173e
9937821 7209_0:00127c
25340757 51031_0:00354b
25352643 51031_0:00305e
25355518 51031_0:0046e6
25355519 51031_0:0046e7
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025