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N-acetyl galactosaminidase, alpha

Summary

Gene Symbol

Naga

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

17939

PubChem

17939

Alliance of Genome Resources

MGI:1261422

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosidase
Lipid metabolism
Lysosome
Phosphoprotein
Reference proteome
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9QWR8	Alpha-galactosidase B
Q3U6T2

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
carbohydrate metabolic process
lipid metabolic process
oligosaccharide metabolic process	IBA
carbohydrate catabolic process	ISS
carbohydrate catabolic process	ISO

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

carbohydrate catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

lipid metabolic process

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

lipid metabolic process

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

glycosyl compound metabolic process [inference]

glycoside metabolic process [inference]

glycoside catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

carbohydrate catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytoplasm	IBA
lysosome	IEA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
hydrolase activity, hydrolyzing O-glycosyl compounds
alpha-galactosidase activity	IBA
alpha-N-acetylgalactosaminidase activity	ISS
alpha-N-acetylgalactosaminidase activity	ISO
protein homodimerization activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds

galactosidase activity [inference]

alpha-galactosidase activity

hexosaminidase activity [inference]

alpha-N-acetylgalactosaminidase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Alpha-galactosidase

Functional Category

G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
alpha-galactosidase activity
hydrolase activity, acting on glycosyl bonds
hydrolase activity

Displaying **all 5** entries
InterPro
Aldolase-type TIM barrel
Alpha galactosidase, C-terminal beta sandwich domain
Glycoside hydrolase superfamily
Glycoside hydrolase, family 27
Glycosyl hydrolase, all-beta

Rhea

RHEA:15085

an N-acetyl-α-D-galactosaminyl-(1→3)-[α-L-fucosyl-(1→2)]-β-D-galactosyl derivative + H₂O

an α-L-fucosyl-(1→2)-β-D-galactosyl derivative + N-acetyl-D-galactosamine

Enzyme

3.2.1.49

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP004592
Gene Name: N-acetyl galactosaminidase, alpha

Ortholog

Displaying entries **1 - 10** of 93 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	2717	FB:FBgn0034117
Homo sapiens	4668	Xenbase:XB-GENE-5832581	HUMAN60864
Drosophila melanogaster	11605	FB:FBgn0034117
Xenopus tropicalis	17939	Xenbase:XB-GENE-5832581
Xenopus tropicalis	179660	Xenbase:XB-GENE-5832581
Rattus norvegicus	315165	Xenbase:XB-GENE-5832581	RATNO38043
Pan troglodytes	470279		PANTR26726
Canis lupus familiaris	481226		CANLF01546
Bos taurus	533357		BOVIN30780
Danio rerio	560778		DANRE35229