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Dopamine receptor 1

Summary

Gene Symbol

dop-1

Organism

Caenorhabditis elegans

External Links

NCBI Gene

180714

PubChem

180714

Alliance of Genome Resources

WB:WBGene00001052

Annotation

Keyword

Cell membrane
G-protein coupled receptor
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q86ME5
Q86ME4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
G protein-coupled receptor signaling pathway	IEA
response to stimulus	IEA
synaptic transmission, dopaminergic	IEA
response to food	IGI	15378064
chemical synaptic transmission	IBA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

synaptic transmission, dopaminergic

signal transduction [inference]

G protein-coupled receptor signaling pathway

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating dopamine receptor signaling pathway

G protein-coupled serotonin receptor signaling pathway

dopamine receptor signaling pathway

adenylate cyclase-activating dopamine receptor signaling pathway

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

nonassociative learning [inference]

habituation

behavior [inference]

learning or memory [inference]

learning [inference]

nonassociative learning [inference]

habituation

mechanosensory behavior

response to stimulus

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to food

response to chemical [inference]

response to food

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

synaptic transmission, dopaminergic

regulation of locomotion

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating dopamine receptor signaling pathway

G protein-coupled serotonin receptor signaling pathway

dopamine receptor signaling pathway

adenylate cyclase-activating dopamine receptor signaling pathway

Displaying **all 4** entries
GO Term	Evidence Code	PMID
dendrite	IBA
synapse	IEA
plasma membrane	IBA IEA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
epinephrine binding	IDA	14739932
signaling receptor activity	IEA
neurotransmitter receptor activity	IBA
dopamine neurotransmitter receptor activity, coupled via Gs	IDA	14739932
G protein-coupled serotonin receptor activity	IBA

GO Hierarchy

molecular function

binding [inference]

ion binding [inference]

cation binding [inference]

norepinephrine binding

organic cyclic compound binding [inference]

catecholamine binding [inference]

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

G protein-coupled amine receptor activity [inference]

G protein-coupled serotonin receptor activity

neurotransmitter receptor activity

postsynaptic neurotransmitter receptor activity [inference]

dopamine neurotransmitter receptor activity [inference]

dopamine neurotransmitter receptor activity, coupled via Gs

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

receptor

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
cell projection	PMID:14568548
plasma membrane	PMID:14568548
neuron projection	PMID:14568548

Disease

Disease Ontology

Displaying entries **1 - 10** of 19 in total

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DO ID	Disease Name	Source
DOID:0050741	alcohol dependence	Alliance of Genome Resources
DOID:0060001	withdrawal disorder	Alliance of Genome Resources
DOID:0060040	pervasive developmental disorder	Alliance of Genome Resources
DOID:0081292	traumatic brain injury	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:1074	kidney failure	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:1094	attention deficit hyperactivity disorder	Alliance of Genome Resources
DOID:12858	Huntington's disease	Alliance of Genome Resources
DOID:14330	Parkinson's disease	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 16 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Homo sapiens	1812		HGNC:3020
Homo sapiens	1816		HGNC:3026
Mus musculus	13488		MGI:99578
Mus musculus	13492		MGI:94927
Rattus norvegicus	24316		RGD:2518
Rattus norvegicus	25195		RGD:2523
Drosophila melanogaster	41726		FB:FBgn0011582
Danio rerio	568126		ZFIN:ZDB-GENE-070524-2
Danio rerio	792634		ZFIN:ZDB-GENE-130522-1
Brugia malayi	6101112	6279_0:00214e

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External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements