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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Disintegrin and metalloproteinase domain-containing protein adm-2
Summary
- Gene Symbol
-
- adm-2
- Organism
- Caenorhabditis elegans
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Disulfide bond
- EGF-like domain
- Endosome
- Glycoprotein
- Lysosome
- Metal-binding
- Metalloprotease
- Reference proteome
- Transmembrane helix
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| G5EDW5 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| membrane protein ectodomain proteolysis |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| endosome | ||
| lysosome | ||
| endosome membrane | ||
| lysosomal membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| metalloendopeptidase activity | ||
| metallopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Disintegrin
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| InterPro |
|---|
| ADAM, cysteine-rich domain |
| Disintegrin domain superfamily |
| Disintegrin domain |
| Metallopeptidase, catalytic domain superfamily |
| Peptidase M12B, ADAM/reprolysin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060075 | estrogen-receptor positive breast cancer | |
| DOID:0111020 | cone-rod dystrophy 9 | |
| DOID:10652 | Alzheimer's disease | |
| DOID:1612 | breast cancer | |
| DOID:1793 | pancreatic cancer | |
| DOID:1824 | status epilepticus | |
| DOID:2841 | asthma | |
| DOID:3008 | invasive ductal carcinoma | |
| DOID:3083 | chronic obstructive pulmonary disease | |
| DOID:3459 | breast carcinoma |
