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neuropeptide Y receptor Y1

Summary

Gene Symbol

Npy1r

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

18166

PubChem

18166

Alliance of Genome Resources

MGI:104963

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q04573
Q3V1K5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 15** of 17 in total

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GO Term	Evidence Code	PMID
neuropeptide signaling pathway	IDA	10698177
regulation of presynaptic cytosolic calcium ion concentration	ISO
signal transduction	IEA
peristalsis	ISO
regulation of multicellular organism growth	IMP	9861026

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

synaptic signaling via neuropeptide

signal transduction

G protein-coupled receptor signaling pathway

neuropeptide signaling pathway

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

smooth muscle contraction [inference]

phasic smooth muscle contraction [inference]

peristalsis

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

nervous system process [inference]

sensory perception [inference]

sensory perception of pain

behavior [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

outflow tract morphogenesis

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

neuron cellular homeostasis [inference]

regulation of presynaptic cytosolic calcium ion concentration

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

negative regulation of signaling [inference]

negative regulation of hormone secretion

regulation of hormone secretion [inference]

negative regulation of hormone secretion

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion [inference]

regulation of synaptic vesicle exocytosis

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

synaptic signaling via neuropeptide

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of synaptic vesicle exocytosis

regulation of hormone secretion [inference]

negative regulation of hormone secretion

regulation of neurotransmitter secretion [inference]

regulation of synaptic vesicle exocytosis

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter secretion [inference]

regulation of synaptic vesicle exocytosis

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of synaptic vesicle exocytosis

regulation of growth [inference]

regulation of developmental growth [inference]

regulation of multicellular organism growth

positive regulation of biological process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of vasoconstriction

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of hormone secretion

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of hormone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of multicellular organism growth

regulation of cellular process [inference]

signal transduction

G protein-coupled receptor signaling pathway

neuropeptide signaling pathway

regulation of cell communication [inference]

negative regulation of cell communication [inference]

negative regulation of hormone secretion

regulation of hormone secretion [inference]

negative regulation of hormone secretion

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion [inference]

regulation of synaptic vesicle exocytosis

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of hormone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of synaptic vesicle exocytosis

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of synaptic vesicle exocytosis

regulation of hormone secretion [inference]

negative regulation of hormone secretion

regulation of neurotransmitter secretion [inference]

regulation of synaptic vesicle exocytosis

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion

regulation of multicellular organismal process [inference]

regulation of multicellular organism growth

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

positive regulation of multicellular organismal process [inference]

positive regulation of vasoconstriction

regulation of biological quality [inference]

regulation of blood pressure

regulation of hormone levels [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion

negative regulation of cytosolic calcium ion concentration

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
glutamatergic synapse	ISO
synaptic vesicle	ISO
axon	ISO
neuronal dense core vesicle	ISO
neuron projection	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

axon

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

secretory granule [inference]

dense core granule [inference]

neuronal dense core vesicle

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

secretory granule [inference]

dense core granule [inference]

neuronal dense core vesicle

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

secretory granule [inference]

dense core granule [inference]

neuronal dense core vesicle

exocytic vesicle [inference]

synaptic vesicle

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
pancreatic polypeptide receptor activity	IDA	10698177
neuropeptide binding	IBA
neuropeptide Y receptor activity	IDA	10698177
neuropeptide receptor activity	IBA
G protein-coupled receptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

amide binding [inference]

peptide binding [inference]

neuropeptide binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

neuropeptide Y receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

neuropeptide Y receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying entries **1 - 10** of 14 in total

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DO ID	Disease Name	Source
DOID:0050742	nicotine dependence	Alliance of Genome Resources
DOID:0050830	peripheral artery disease	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:11832	visual epilepsy	Alliance of Genome Resources
DOID:1574	alcohol use disorder	Alliance of Genome Resources
DOID:1596	depressive disorder	Alliance of Genome Resources
DOID:1825	childhood absence epilepsy	Alliance of Genome Resources
DOID:2030	anxiety disorder	Alliance of Genome Resources
DOID:2559	opiate dependence	Alliance of Genome Resources
DOID:3328	temporal lobe epilepsy	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of 83 in total

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Species	Gene ID	Orthologous MAtrix
Mustela putorius furo	101681510	MUSPF03552
Felis catus	101099875	FELCA09230
Panthera leo	122217740	PANLE26841
Tursiops truncatus	101322323	TURTR01359
Balaenoptera musculus	118895631	BALMU27618
Loxodonta africana	100668572	LOXAF05851
Equus caballus	100061686	HORSE27605
Sus scrofa	397547	PIGXX33653
Bos taurus	504813	BOVIN30990
Capra hircus	102186285	CAPHI25974