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dual specificity tyrosine phosphorylation regulated kinase 1A

Summary

Gene Symbol

DYRK1A

Organism

Homo sapiens (human)

External Links

NCBI Gene

1859

PubChem

1859

Alliance of Genome Resources

HGNC:3091

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Host-virus interaction
Intellectual disability
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Serine/threonine-protein kinase
Transcription regulation
Tyrosine-protein kinase

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q13627	Dual specificity YAK1-related kinase HP86 Protein kinase minibrain homolog
A0A2R8Y6I6	Protein kinase minibrain homolog

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 26 in total

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GO Term	Evidence Code	PMID
chromatin remodeling	IEA
regulation of transcription by RNA polymerase II	IEA
protein phosphorylation	ISS
protein phosphorylation	TAS	24327345 28377597
nervous system development	TAS	8769099

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process [inference]

amyloid-beta metabolic process [inference]

amyloid-beta formation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

amyloid-beta metabolic process [inference]

amyloid-beta formation

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-serine autophosphorylation

peptidyl-threonine phosphorylation

peptidyl-tyrosine phosphorylation

peptidyl-tyrosine autophosphorylation

protein autophosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

peptidyl-serine autophosphorylation

peptidyl-threonine modification [inference]

peptidyl-threonine phosphorylation

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

peptidyl-tyrosine autophosphorylation

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process [inference]

amyloid-beta formation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-serine autophosphorylation

peptidyl-threonine phosphorylation

peptidyl-tyrosine phosphorylation

peptidyl-tyrosine autophosphorylation

protein autophosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-serine autophosphorylation

peptidyl-threonine phosphorylation

peptidyl-tyrosine phosphorylation

peptidyl-tyrosine autophosphorylation

protein autophosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

peptidyl-serine autophosphorylation

peptidyl-threonine modification [inference]

peptidyl-threonine phosphorylation

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

peptidyl-tyrosine autophosphorylation

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process [inference]

amyloid-beta formation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-serine autophosphorylation

peptidyl-threonine phosphorylation

peptidyl-tyrosine phosphorylation

peptidyl-tyrosine autophosphorylation

protein autophosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

peptidyl-serine autophosphorylation

peptidyl-threonine modification [inference]

peptidyl-threonine phosphorylation

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

peptidyl-tyrosine autophosphorylation

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process [inference]

amyloid-beta formation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-serine autophosphorylation

peptidyl-threonine phosphorylation

peptidyl-tyrosine phosphorylation

peptidyl-tyrosine autophosphorylation

protein autophosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

peptidyl-serine autophosphorylation

peptidyl-threonine modification [inference]

peptidyl-threonine phosphorylation

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

peptidyl-tyrosine autophosphorylation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

amyloid-beta metabolic process [inference]

amyloid-beta formation

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-serine autophosphorylation

peptidyl-threonine phosphorylation

peptidyl-tyrosine phosphorylation

peptidyl-tyrosine autophosphorylation

protein autophosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

peptidyl-serine autophosphorylation

peptidyl-threonine modification [inference]

peptidyl-threonine phosphorylation

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

peptidyl-tyrosine autophosphorylation

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process [inference]

amyloid-beta formation

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-serine autophosphorylation

peptidyl-threonine phosphorylation

peptidyl-tyrosine phosphorylation

peptidyl-tyrosine autophosphorylation

protein autophosphorylation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

rhythmic process [inference]

circadian rhythm

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of heterochromatin formation [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

regulation of DNA methylation-dependent heterochromatin formation [inference]

negative regulation of DNA methylation-dependent heterochromatin formation

regulation of RNA splicing [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of RNA splicing

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein deacetylation

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein deacetylation

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of RNA splicing

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of heterochromatin formation [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

regulation of DNA methylation-dependent heterochromatin formation [inference]

negative regulation of DNA methylation-dependent heterochromatin formation

regulation of RNA splicing [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of RNA splicing

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of RNA splicing

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein deacetylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein deacetylation

regulation of protein deacetylation [inference]

positive regulation of protein deacetylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein deacetylation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of heterochromatin formation [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

regulation of DNA methylation-dependent heterochromatin formation [inference]

negative regulation of DNA methylation-dependent heterochromatin formation

regulation of RNA splicing [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of RNA splicing

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein deacetylation

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein deacetylation

regulation of protein deacetylation [inference]

positive regulation of protein deacetylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein deacetylation

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of RNA splicing

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of RNA splicing

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein deacetylation

regulation of protein deacetylation [inference]

positive regulation of protein deacetylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein deacetylation

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of signal transduction by p53 class mediator [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein deacetylation

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein deacetylation

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of supramolecular fiber organization [inference]

negative regulation of microtubule polymerization

negative regulation of chromatin organization [inference]

negative regulation of heterochromatin organization [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of signal transduction by p53 class mediator [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of signal transduction by p53 class mediator [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of RNA splicing

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of heterochromatin formation [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

regulation of DNA methylation-dependent heterochromatin formation [inference]

negative regulation of DNA methylation-dependent heterochromatin formation

regulation of RNA splicing [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of RNA splicing

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of microtubule-based process [inference]

regulation of microtubule cytoskeleton organization [inference]

regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

regulation of microtubule polymerization [inference]

negative regulation of microtubule polymerization

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

regulation of protein polymerization [inference]

regulation of microtubule polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of supramolecular fiber organization [inference]

negative regulation of microtubule polymerization

negative regulation of chromatin organization [inference]

negative regulation of heterochromatin organization [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

regulation of cytoskeleton organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

regulation of microtubule cytoskeleton organization [inference]

regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

regulation of microtubule polymerization [inference]

negative regulation of microtubule polymerization

regulation of protein-containing complex assembly [inference]

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

regulation of protein polymerization [inference]

regulation of microtubule polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of supramolecular fiber organization [inference]

negative regulation of microtubule polymerization

negative regulation of chromatin organization [inference]

negative regulation of heterochromatin organization [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

regulation of chromatin organization [inference]

regulation of heterochromatin organization [inference]

regulation of heterochromatin formation [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

regulation of DNA methylation-dependent heterochromatin formation [inference]

negative regulation of DNA methylation-dependent heterochromatin formation

negative regulation of heterochromatin organization [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

negative regulation of chromatin organization [inference]

negative regulation of heterochromatin organization [inference]

negative regulation of heterochromatin formation

negative regulation of DNA methylation-dependent heterochromatin formation

regulation of supramolecular fiber organization [inference]

regulation of microtubule polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of supramolecular fiber organization [inference]

negative regulation of microtubule polymerization

regulation of cellular response to stress [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

negative regulation of DNA damage response, signal transduction by p53 class mediator

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
nucleus	ISS
nucleus	IDA	15694837 23415227 25620562
nucleus	IBA
nucleoplasm	TAS
nucleoplasm	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

ribonucleoprotein complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

cytosol

nuclear body [inference]

nuclear speck

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

intermediate filament [inference]

neurofilament

actin filament

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
transcription coactivator activity	IBA
actin binding	IPI	24327345
protein kinase activity	TAS	8769099 8975710
protein serine/threonine kinase activity	ISS	20736167
protein serine/threonine kinase activity	NAS	28386764

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein serine/threonine kinase activity

protein serine/threonine/tyrosine kinase activity

protein tyrosine kinase activity

non-membrane spanning protein tyrosine kinase activity

histone kinase activity [inference]

histone H3 kinase activity [inference]

histone H3T45 kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein serine/threonine kinase activity

protein serine/threonine/tyrosine kinase activity

protein tyrosine kinase activity

non-membrane spanning protein tyrosine kinase activity

histone kinase activity [inference]

histone H3 kinase activity [inference]

histone H3T45 kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein serine/threonine kinase activity

protein serine/threonine/tyrosine kinase activity

protein tyrosine kinase activity

non-membrane spanning protein tyrosine kinase activity

histone kinase activity [inference]

histone H3 kinase activity [inference]

histone H3T45 kinase activity

histone modifying activity [inference]

histone kinase activity [inference]

histone H3 kinase activity [inference]

histone H3T45 kinase activity

RNA polymerase II CTD heptapeptide repeat modifying activity [inference]

RNA polymerase II CTD heptapeptide repeat kinase activity

binding [inference]

protein binding

cytoskeletal protein binding

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

transcription regulator activity [inference]

transcription coregulator activity [inference]

transcription coactivator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

dual specificity tyrosine-phosphorylation-regulated kinase

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ATP binding
nucleotide binding
protein serine/threonine/tyrosine kinase activity

Displaying **all 5** entries
InterPro
Dual specificity tyrosine-phosphorylation-regulated kinase 1A/1B, catalytic domain
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine/threonine-protein kinase, active site

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0060041	autism spectrum disorder	Alliance of Genome Resources
DOID:0070037	autosomal dominant intellectual developmental disorder 7	Alliance of Genome Resources
DOID:1059	intellectual disability	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	1859	Xenbase:XB-GENE-1017105
Mus musculus	13548		MOUSE18241
Drosophila melanogaster	13549	FB:FBgn0259168
Rattus norvegicus	25255		RATNO04730
Xenopus tropicalis	32771	Xenbase:XB-GENE-1017105
Pan troglodytes	458545		PANTR25671
Canis lupus familiaris	487755		CANLF12870
Macaca mulatta	693812		MACMU30630
Danio rerio	853300	ZFIN:ZDB-GENE-030131-5677
Monodelphis domestica	100019775		MONDO21684

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements