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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
angiotensin II receptor type 1
Summary
- Gene Symbol
-
- AGTR1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Disease variant
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Host-virus interaction
- Palmitate
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| D3DNG8 |
|
| P30556 |
|
| Q6NUP5 |
|
| A0A0A0MSE3 |
|
| Q53YY0 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis | ||
| viral entry into host cell | ||
| positive regulation of macrophage derived foam cell differentiation | ||
| phospholipase C-activating G protein-coupled receptor signaling pathway | ||
| inflammatory response |
GO Hierarchy
biological process
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| angiotensin type I receptor activity | ||
| protein heterodimerization activity | ||
| bradykinin receptor binding | ||
| angiotensin type II receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- type-1 angiotensin ii receptor
- Functional Category
-
- K: Transcription
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| C-C chemokine binding |
| C-C chemokine receptor activity |
| angiotensin type I receptor activity |
| angiotensin type II receptor activity |
| angiotensin-activated signaling pathway |
| brain development |
| calcium-mediated signaling |
| cell chemotaxis |
| immune response |
| neurogenesis |
| InterPro |
|---|
| Angiotensin II receptor family |
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3393 | coronary artery disease | |
| DOID:3407 | carotid artery disease | |
| DOID:3891 | placental insufficiency | |
| DOID:4450 | renal cell carcinoma | |
| DOID:4780 | anti-basement membrane glomerulonephritis | |
| DOID:576 | proteinuria | |
| DOID:6000 | congestive heart failure | |
| DOID:6432 | pulmonary hypertension | |
| DOID:6713 | cerebrovascular disease | |
| DOID:784 | chronic kidney disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 460762 | 9598_0:00111c | PANTR32398 | ||
| 712773 | MACMU28948 | |||
| 794575 | ZFIN:ZDB-GENE-070912-546 | DANRE28969 | ||
| 100009164 | RABIT04456 | |||
| 100017858 | MONDO31505 | |||
| 100059005 | HORSE11891 | |||
| 100077014 | ORNAN11859 | |||
| 100170183 | Xenbase:XB-GENE-478953 | |||
| 100192325 | CAVPO04780 | |||
| 100224975 | TAEGU30475 |
