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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
NAD(P)H oxidase (H2O2-forming)
Summary
- Gene Symbol
-
- duox-2
- Organism
- Caenorhabditis elegans
Annotation
- Keyword
-
- Calcium
- FAD
- Glycoprotein
- Heme
- NADP
- Oxidoreductase
- Reference proteome
- Repeat
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| O01795 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| superoxide anion generation | ||
| cuticle development involved in collagen and cuticulin-based cuticle molting cycle | ||
| post-embryonic body morphogenesis | ||
| defense response | ||
| cellular oxidant detoxification |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| NADPH oxidase complex | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium ion binding |
|
|
| NAD(P)H oxidase H2O2-forming activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Dual oxidase
- Functional Category
-
- P: Inorganic ion transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| Haem peroxidase, animal-type |
| Riboflavin synthase-like beta-barrel |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050328 | congenital hypothyroidism | |
| DOID:0050338 | primary bacterial infectious disease | |
| DOID:0112189 | thyroid dyshormonogenesis 6 | |
| DOID:1459 | hypothyroidism | |
| DOID:1498 | cholera | |
| DOID:8577 | ulcerative colitis | |
| DOID:8778 | Crohn's disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 25342565 | 51031_0:001d92 | |||
| 36380437 | 34506_0:000fc6 | |||
| 100486050 | Xenbase:XB-GENE-6047411 |
