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MIRAGE
ATP-binding cassette, sub-family B member 4
Summary
- Gene Symbol
-
- Abcb4
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Cytoplasm
- Cytoplasmic vesicle
- Glycoprotein
- Lipid transport
- Phosphoprotein
- Reference proteome
- Repeat
- Translocase
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P21440 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| xenobiotic transmembrane transport | ||
| positive regulation of cholesterol transport | ||
| positive regulation of cholesterol transport | ||
| bile acid secretion | ||
| phospholipid translocation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi membrane | ||
| nucleoplasm | ||
| nucleoplasm | ||
| cytoplasm | ||
| cytoplasm |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| ATP binding | ||
| ATP hydrolysis activity | ||
| ATPase-coupled transmembrane transporter activity | ||
| ATPase-coupled transmembrane transporter activity | ||
| ATPase-coupled transmembrane transporter activity |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- phosphatidylcholine translocator ABCB4
- Functional Category
-
- E: Amino acid transport and metabolism
- P: Inorganic ion transport and metabolism
- V: Defense mechanisms
| Gene Ontology |
|---|
| ABC-type oligopeptide transporter activity |
| ABC-type transporter activity |
| ATP binding |
| nucleotide binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060643 | primary sclerosing cholangitis | |
| DOID:13580 | cholestasis | |
| DOID:1852 | intrahepatic cholestasis | |
| DOID:1949 | cholecystitis | |
| DOID:684 | hepatocellular carcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 5243 | ZFIN:ZDB-GENE-080204-52 | ||
| 5244 | ZFIN:ZDB-GENE-080204-52 | HUMAN89693 | |
| 8647 | SGD:S000001692 | ||
| 18669 | ZFIN:ZDB-GENE-080204-52 | ||
| 18670 | ZFIN:ZDB-GENE-080204-52 | ||
| 18671 | ZFIN:ZDB-GENE-080204-52 | ||
| 24891 | ZFIN:ZDB-GENE-080204-52 | RATNO30604 | |
| 27413 | SGD:S000001692 | ||
| 36428 | ZFIN:ZDB-GENE-080204-52 | ||
| 38726 | ZFIN:ZDB-GENE-080204-52 |
