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MIRAGE
phosphate regulating endopeptidase homolog, X-linked
Summary
- Gene Symbol
-
- Phex
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Biomineralization
- Cell membrane
- Disulfide bond
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Zinc
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| proteolysis | ||
| protein processing | ||
| organophosphate metabolic process | ||
| bone mineralization |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum | ||
| Golgi apparatus | ||
| plasma membrane | ||
| plasma membrane | ||
| perinuclear region of cytoplasm |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metalloendopeptidase activity | ||
| metalloendopeptidase activity | ||
| metal ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- phosphate-regulating neutral endopeptidase
- Functional Category
-
- K: Transcription
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| InterPro |
|---|
| Metallopeptidase, catalytic domain superfamily |
| Peptidase M13, C-terminal domain |
| Peptidase M13, N-terminal domain |
| Peptidase M13, domain 2 |
| Peptidase M13 |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050445 | X-linked hypophosphatemic rickets | |
| DOID:10754 | otitis media |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 4311 | FB:FBgn0038818 | ||
| 5251 | ZFIN:ZDB-GENE-030103-2 | HUMAN100028 | |
| 17380 | FB:FBgn0038818 | ||
| 18675 | ZFIN:ZDB-GENE-030103-2 | ||
| 24590 | FB:FBgn0038818 | ||
| 25512 | RATNO45722 | ||
| 27390 | FB:FBgn0029843 | ||
| 31547 | ZFIN:ZDB-GENE-030103-2 | ||
| 42449 | ZFIN:ZDB-GENE-030103-2 | ||
| 79258 | FB:FBgn0038818 |
