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MIRAGE
polycystin 1, transient receptor potential channel interacting
Summary
- Gene Symbol
-
- Pkd1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Autocatalytic cleavage
- Cell membrane
- Cilium
- Coiled coil
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Golgi apparatus
- Lectin
- Leucine-rich repeat
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Wnt signaling pathway
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitocytosis | ||
| regulation of G1/S transition of mitotic cell cycle | ||
| regulation of G1/S transition of mitotic cell cycle |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
developmental process [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| polycystin complex | ||
| polycystin complex | ||
| polycystin complex | ||
| nucleus | ||
| cytoplasm |
| GO Term | Evidence Code | PMID |
|---|---|---|
| monoatomic cation channel activity | ||
| calcium channel activity | ||
| calcium channel activity | ||
| calcium channel activity | ||
| protein binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Polycystin-1
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| calcium ion transport |
| kidney development |
| InterPro |
|---|
| C-type lectin-like |
| GPS motif |
| Immunoglobulin-like fold |
| PKD domain superfamily |
| PKD domain |
| PKD/Chitinase domain |
| PKD/REJ-like domain |
| PLAT/LH2 domain superfamily |
| PLAT/LH2 domain |
| Polycystin cation channel, PKD1/PKD2 |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110858 | polycystic kidney disease 1 | |
| DOID:0110861 | autosomal recessive polycystic kidney disease | |
| DOID:11984 | hypertrophic cardiomyopathy |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 105709738 | AOTNA20848 | ||
| 105812938 | PROCO03437 | ||
| 105981898 | DIPOR08190 | ||
| 106836276 | EQUAS28117 | ||
| 107594277 | SINGR36125 | ||
| 107598528 | SINGR48486 | ||
| 108258414 | ICTPU21515 | ||
| 109080669 | CYPCA27426 | ||
| 109108304 | CYPCA30269 | ||
| 109314618 | CROPO22953 |
