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BPI fold containing family A, member 1

Summary

Gene Symbol

Bpifa1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

18843

PubChem

18843

Alliance of Genome Resources

MGI:1338036

Annotation

Keyword

3D-structure
Antibiotic
Disulfide bond
Glycoprotein
Innate immunity
Lipid-binding
Reference proteome
Repeat
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P97361	Palate lung and nasal epithelium clone protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
multicellular organismal-level water homeostasis	ISO ISS
antibacterial humoral response	IBA IMP ISO	23499554
negative regulation of single-species biofilm formation in or on host organism	IBA IMP ISO	23499554
immune response in nasopharyngeal-associated lymphoid tissue	IBA
innate immune response	IBA IMP ISO	23499554

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

immune response in gut-associated lymphoid tissue [inference]

immune response in nasopharyngeal-associated lymphoid tissue

humoral immune response [inference]

antimicrobial humoral response [inference]

innate immune response

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

chemical homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

antibacterial humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

immune response [inference]

immune response in gut-associated lymphoid tissue [inference]

immune response in nasopharyngeal-associated lymphoid tissue

humoral immune response [inference]

antimicrobial humoral response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

antibacterial humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

antibacterial humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

regulation of sodium ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport

regulation of biological process involved in symbiotic interaction [inference]

regulation of single-species biofilm formation in or on host organism [inference]

negative regulation of single-species biofilm formation in or on host organism

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport

negative regulation of cellular process [inference]

negative regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of single-species biofilm formation in or on host organism [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of biological quality [inference]

regulation of body fluid levels [inference]

multicellular organismal-level water homeostasis

Displaying **all 3** entries
GO Term	Evidence Code	PMID
microvillus	IEA ISO
extracellular region	ISO ISS
extracellular space	IBA ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

microvillus

Displaying 1 entry
GO Term	Evidence Code	PMID
lipid binding	IEA

GO Hierarchy

molecular function

binding [inference]

lipid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

BPI fold-containing family A member 5

Functional Category

K: Transcription
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
antimicrobial humoral immune response mediated by antimicrobial peptide
immune response in nasopharyngeal-associated lymphoid tissue
lipid binding
negative regulation of single-species biofilm formation in or on host organism

Displaying **all 2** entries
InterPro
Bactericidal permeability-increasing protein, alpha/beta domain superfamily
Lipid-binding serum glycoprotein, N-terminal

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:10754	otitis media	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **106** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	51297		HGNC:15749	HUMAN56535
Rattus norvegicus	246238	10116_1:0011a8	RGD:619818	RATNO26092
Bos taurus	281989			BOVIN05101
Rattus norvegicus	311559	10116_1:00187b
Sus scrofa	449524			PIGXX11592
Pan troglodytes	458177			PANTR24643
Canis lupus familiaris	609982			CANLF09451
Macaca mulatta	714509			MACMU02894
Monodelphis domestica	100032873			MONDO08858
Callithrix jacchus	100406570			CALJA35320