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thymidine phosphorylase
Summary
- Gene Symbol
-
- TYMP
- Aliases
-
- gliostatin
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Angiogenesis
- Chemotaxis
- Developmental protein
- Differentiation
- Direct protein sequencing
- Disease variant
- Glycosyltransferase
- Growth factor
- Neuropathy
- Phosphoprotein
- Progressive external ophthalmoplegia
- Reference proteome
- Repeat
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell differentiation | ||
| dTMP catabolic process |
GO Hierarchy
- signal transduction
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
catabolic process [inference]
cellular catabolic process [inference]
organic substance catabolic process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
aromatic compound catabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
cellular catabolic process [inference]
heterocycle metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
heterocycle catabolic process [inference]
primary metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
organophosphate metabolic process [inference]
carbohydrate derivative metabolic process [inference]
organic cyclic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
organic cyclic compound catabolic process [inference]
organonitrogen compound metabolic process [inference]
organic substance catabolic process [inference]
cellular process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
aromatic compound catabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
cellular catabolic process [inference]
heterocycle metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
heterocycle catabolic process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| thymidine phosphorylase activity | ||
| protein homodimerization activity | ||
| growth factor activity | ||
| protein binding | ||
| pyrimidine-nucleoside phosphorylase activity |
|
GO Hierarchy
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3652 | Leigh disease | |
| DOID:3683 | lung benign neoplasm | |
| DOID:374 | nutrition disease | |
| DOID:3744 | cervical squamous cell carcinoma | |
| DOID:3748 | esophagus squamous cell carcinoma | |
| DOID:3904 | bronchus carcinoma | |
| DOID:3905 | lung carcinoma | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:3969 | thyroid gland papillary carcinoma | |
| DOID:3973 | thyroid gland medullary carcinoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0007108 | Demyelinating peripheral neuropathy |
| HP:0007141 | Sensorimotor neuropathy |
| HP:0008049 | Abnormality of the extraocular muscles |
| HP:0009027 | Foot dorsiflexor weakness |
| HP:0009830 | Peripheral neuropathy |
| HP:0011024 | Abnormality of the gastrointestinal tract |
| HP:0012103 | Abnormality of the mitochondrion |
| HP:0012533 | Allodynia |
| HP:0012850 | Small intestinal dysmotility |
| HP:0100613 | Death in early adulthood |
| Disease ID | Disease Name |
|---|---|
| ORPHA:298 |
|
| OMIM:603041 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 102359893 | LATCH07847 | ||
| 103910413 | ZFIN:ZDB-GENE-100415-1 | ||
| 103037194 | ASTMX07104 | ||
| 113584422 | ELEEL32709 | ||
| 105024878 | ESOLU54576 | ||
| 100195250 | SALSA51758 | ||
| 115188366 | SALTR47533 | ||
| 115188367 | SALTR47533 | ||
| 115188413 | SALTR47533 | ||
| 115188414 | SALTR47511 |
