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thymidine phosphorylase
Summary
- Gene Symbol
-
- TYMP
- Aliases
-
- gliostatin
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Angiogenesis
- Chemotaxis
- Developmental protein
- Differentiation
- Direct protein sequencing
- Disease variant
- Glycosyltransferase
- Growth factor
- Neuropathy
- Phosphoprotein
- Progressive external ophthalmoplegia
- Reference proteome
- Repeat
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of transmission of nerve impulse | ||
| regulation of gastric motility |
GO Hierarchy
- signal transduction
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
catabolic process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
cellular catabolic process [inference]
heterocycle metabolic process [inference]
primary metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
organophosphate metabolic process [inference]
carbohydrate derivative metabolic process [inference]
organic cyclic compound metabolic process [inference]
organic substance catabolic process [inference]
cellular process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
cellular catabolic process [inference]
heterocycle metabolic process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| 1,4-alpha-oligoglucan phosphorylase activity | ||
| protein binding | ||
| growth factor activity | ||
| thymidine phosphorylase activity | ||
| thymidine phosphorylase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- thymidine phosphorylase
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- H: Coenzyme transport and metabolism
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080119 | mitochondrial DNA depletion syndrome 1 | |
| DOID:1793 | pancreatic cancer | |
| DOID:2671 | transitional cell carcinoma | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:890 | mitochondrial encephalomyopathy |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0003270 | Abdominal distention |
| HP:0003348 | Hyperalaninemia |
| HP:0003387 | Decreased number of large peripheral myelinated nerve fibers |
| HP:0003388 | Easy fatigability |
| HP:0003401 | Paresthesia |
| HP:0003431 | Decreased motor nerve conduction velocity |
| HP:0003448 | Decreased sensory nerve conduction velocity |
| HP:0003477 | Peripheral axonal neuropathy |
| HP:0003548 | Subsarcolemmal accumulations of abnormally shaped mitochondria |
| HP:0003621 | Juvenile onset |
| Disease ID | Disease Name |
|---|---|
| ORPHA:298 |
|
| OMIM:603041 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 115542463 | GADMO44961 | ||
| 115595786 | SPAAU48961 | ||
| 117028157 | RHIFE08848 | ||
| 118287390 | SCOMX21537 | ||
| 129529456 | GORGO24238 |
