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thymidine phosphorylase
Summary
- Gene Symbol
-
- TYMP
- Aliases
-
- gliostatin
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Angiogenesis
- Chemotaxis
- Developmental protein
- Differentiation
- Direct protein sequencing
- Disease variant
- Glycosyltransferase
- Growth factor
- Neuropathy
- Phosphoprotein
- Progressive external ophthalmoplegia
- Reference proteome
- Repeat
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of transmission of nerve impulse | ||
| regulation of gastric motility |
GO Hierarchy
- signal transduction
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
catabolic process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
cellular catabolic process [inference]
heterocycle metabolic process [inference]
primary metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
organophosphate metabolic process [inference]
carbohydrate derivative metabolic process [inference]
organic cyclic compound metabolic process [inference]
organic substance catabolic process [inference]
cellular process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
cellular catabolic process [inference]
heterocycle metabolic process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| 1,4-alpha-oligoglucan phosphorylase activity | ||
| protein binding | ||
| growth factor activity | ||
| thymidine phosphorylase activity | ||
| thymidine phosphorylase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Dioxygenase
- Functional Category
-
- G: Carbohydrate transport and metabolism
- K: Transcription
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| phytanoyl-CoA dioxygenase activity |
| InterPro |
|---|
| Phytanoyl-CoA dioxygenase-like |
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080119 | mitochondrial DNA depletion syndrome 1 | |
| DOID:1793 | pancreatic cancer | |
| DOID:2671 | transitional cell carcinoma | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:890 | mitochondrial encephalomyopathy |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000044 | Hypogonadotropic hypogonadism |
| HP:0000407 | Sensorineural hearing impairment |
| HP:0000508 | Ptosis |
| HP:0000544 | External ophthalmoplegia |
| HP:0000590 | Progressive external ophthalmoplegia |
| HP:0000597 | Ophthalmoparesis |
| HP:0000651 | Diplopia |
| HP:0000726 | Dementia |
| HP:0000815 | Hypergonadotropic hypogonadism |
| Disease ID | Disease Name |
|---|---|
| ORPHA:298 |
|
| OMIM:603041 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 102784011 | NEOBR01259 | ||
| 103037194 | ASTMX07104 | ||
| 103154276 | POEFO18559 | ||
| 103164808 | ORNAN05738 | ||
| 103223569 | CHLSB07456 | ||
| 103382511 | CYNSE28518 | ||
| 103735486 | NANGA18165 | ||
| 105024878 | ESOLU54576 | ||
| 105489744 | MACNE38821 | ||
| 105586866 | CERAT33492 |
